MedPath

Evaluation of morphological and functional outcome of early leaflet thrombosis after TAVI

Recruiting
Conditions
eaflet thrombosis after TAVI
Registration Number
DRKS00023520
Lead Sponsor
niversitätsherzzentrum Freiburg-Bad Krozingen
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
20
Inclusion Criteria

• Intervention at least 2 years ago
• Existing post-interventional CT diagnostics during the implantation stay
• Consent to participate in the study with CT implementation
•> 59. age

Exclusion Criteria

Lack of consent
• Oral anticoagulation

Study & Design

Study Type
observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The primary endpoint is the quantitative measurement of possible calcification of the prosthetic cusps using CT.
Secondary Outcome Measures
NameTimeMethod
-Density measurement of the prosthetic cusps derived from the CT.<br>- Thickening or hypomobility of the cusps of the prosthesis.<br>- Limitation of mobility of the prosthesis cups.<br>- Deterioration of functional valve parameters in echocardiography (maximum speed, mean / maximum pressure gradient, speed quotient, aortic valve prosthesis opening area index, transvalvular and paravalvular insufficiency)<br>- Clinical parameters such as stroke / TIA rate, systemic embolism, myocardial infarction, hospitalization for heart failure, syncope, NYHA status changes<br><br>
© Copyright 2025. All Rights Reserved by MedPath