Effect of magnesium sulphate on emergence delirium in pediatric patient undergoing infraumbilical surgery: a double blinded randomized controlled trial
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 72
- 试验地点
- 1
- 主要终点
- To assess the effects of Magnesium Sulphate on the incidence of emergence
研究概览
简要总结
Magnesium sulphate, an NMDA receptor antagonist, possesses sedative, analgesic, and anti-agitation properties. Emergence delirium (ED) is a common postoperative complication in children receiving sevoflurane anaesthesia, especially after infraumbilical surgeries, leading to agitation, restlessness, and risk of injury. Current management often relies on opioids and sedatives, which increase side effects. Pre-emptive intravenous magnesium sulphate may reduce the incidence and severity of ED, decrease analgesic requirements, and improve recovery profiles in children.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 2.00 Year(s) 至 8.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Paediatric patient age 2-8 years
- •Patient scheduled for elective infraumbilical surgeries
- •ASA I and II.
排除标准
- •1.History of hypersensitivity
- •Neurological disorders, developmental delay, or psychiatric illness
- •pre-existing electrolyte imbalance
- •cardiac conduction abnormalities
- •Neuromuscular disease pulmonary, hepatobiliary or renal disease..
结局指标
主要结局
To assess the effects of Magnesium Sulphate on the incidence of emergence
时间窗: Just before induction till postoperative period of 60 minutes
delirium in pediatric patients undergoing elective infraumbilical surgery using PAED score
时间窗: Just before induction till postoperative period of 60 minutes
次要结局
- 1.To assess severity of emergence delirium using PAED score.(2. To assess and evaluate post operative pain score using FLACC score.)
研究者
Tanveer Singh Aulakh
AIIMS PATNA