A Comparison of the Effects of Different Periodization-Based Strength Training Programs in Individuals With Type 2 Diabetes Mellitus
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 48
- 试验地点
- 1
- 主要终点
- Exercise Capacity
研究概览
简要总结
This randomized controlled study aims to compare the effects of different periodization-based strength training approaches in individuals with type 2 diabetes mellitus. Participants will be allocated to non-linear periodization, linear periodization, or control groups. The intervention program will be conducted for 8 weeks and will evaluate exercise capacity, muscle strength, quality of life, body composition, and metabolic parameters.
详细描述
Type 2 diabetes mellitus is associated with reduced exercise capacity, decreased muscle strength, impaired quality of life, and metabolic dysfunction. Exercise training is recommended as an important component of diabetes management; however, the comparative effectiveness of different strength training periodization approaches remains unclear.
This randomized controlled trial aims to compare the effects of non-linear periodization and linear periodization strength training programs in individuals with type 2 diabetes mellitus. Participants will be randomized into three groups: a non-linear periodization training group, a linear periodization training group, and a control group receiving usual care.
The intervention will be conducted for 8 weeks, three times per week. Outcomes including exercise capacity, muscle strength, body composition, quality of life, and metabolic parameters will be evaluated before and after the intervention period.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults aged between 18 to 65 years
- •Diagnosis of Type 2 Diabetes Mellitus (T2DM)
- •Not having participated in any structured exercise program within the last 6 months
- •Willingness to participate in the study and provide written informed consent
排除标准
- •Presence of nephropathy, retinopathy, or peripheral neuropathy
- •Presence of neurological, cognitive, or orthopedic disorders that may affect outcome measurements
- •Severe respiratory disease (Forced Expiratory Volume in the first second [FEV1] <35% or Forced Vital Capacity [FVC] <50%)
- •Presence of ischemic heart disease or peripheral arterial disease
- •History of any cardiovascular event within the last 6 months
- •Current malignancy
研究组 & 干预措施
Non-linear Periodization Group
Participants will receive non-linear periodization-based strength training three times per week for 8 weeks.
干预措施: Non-linear Periodization-Based Strength Training (Behavioral)
Linear Periodization Group
Participants will receive linear periodization-based strength training three times per week for 8 weeks.
干预措施: Linear Periodization-Based Strength Training (Behavioral)
Control Group
Participants will receive usual care and no structured exercise intervention during the study period.
干预措施: Usual Care (Other)
结局指标
主要结局
Exercise Capacity
时间窗: Baseline and after 8 week
Exercise capacity will be assessed using the 6-Minute Walk Test (6MWT)
次要结局
- Change in Peripheral Muscle Strength(Baseline and after 8 weeks)
- Change in Hand Grip Strength(Baseline and after 8 weeks)
- Change in Diabetes Quality of Life Questionnaire Score(Baseline and after 8 weeks)
- Change in Body Fat Percentage(Baseline and after 8 weeks)
- Change in Skeletal Muscle Mass(Baseline and after 8 weeks)
- Change in Resting Metabolic Rate(Baseline and after 8 weeks)
- Change in Hemoglobin A1c (HbA1c)(Baseline and after 8 weeks)
- Change in Fasting Blood Glucose(Baseline and after 8 weeks)
研究者
Neslihan Duruturk
Prof. Dr.
Baskent University