Feasibility and efficacy of the de-escalation therapy by Biapenem for postoperative bacterial pneumonia.
Not Applicable
Recruiting
- Conditions
- postoperative pneumonia after esophagectomy for esophageal cancer
- Registration Number
- JPRN-UMIN000017219
- Lead Sponsor
- Department of Gastrointestinal Surgery, The University of Tokyo Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Not provided
Exclusion Criteria
Other infectious disease including SSI is present. History of hyper reactive events caused by carbapenem. The suspected pathogenic microbes of the pneumonia is; MRSA, MDRP, virus, mycoplasma, regionera, clmamigia, MAC, yeast. MRSA or MDRP is present in any culture specimen during the in hospital course. History of epilepsy or barproic acid use. Renal disease with Ccr lower than 20ml/kg.min or requiring hemodialysis.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Days required for the treatment of Biapenem Postoperative hospital stay
- Secondary Outcome Measures
Name Time Method Clinical and bacteriological efficacy rates at each time point during the use of Biapanem.