Postoperative Analgesia in patients of Anterior Cervical Discectomy and Fusion (ACDF) Surgery
Not Applicable
Completed
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2020/12/030091
- Lead Sponsor
- Dr Tarun Singh
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 83
Inclusion Criteria
Patients of ASA physical status I and II, aged 18 to 65 years with of BMI <30 with cervical disc prolapse scheduled for single or multiple level anterior cervical discectomy and fusion.
Exclusion Criteria
Patients who have traumatic cervical spine injury, underwent prior cervical disc surgery, prior respiratory compromise, preoperative opioid or steroids use, hypersensitivity to the subject drugs and patients whose mental status will affect the completion of the QoR-15 questionnaire.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie ketamine's analgesic effects compared to fentanyl in ACDF surgery patients?
How does ketamine infusion compare to standard opioid analgesia for postoperative pain management in ACDF trials?
Are there specific biomarkers like CYP2D6 or OPRM1 polymorphisms predicting response to ketamine vs. fentanyl in cervical spine surgery?
What adverse events are associated with ketamine versus fentanyl infusions in CTRI/2020/12/030091 ACDF trial and how are they managed?
What combination therapies or alternative NMDA receptor antagonists show promise alongside ketamine for enhanced postoperative analgesia in ACDF?