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临床试验/CTRI/2025/07/091312
CTRI/2025/07/091312尚未招募Phase 3 4

Evaluation of Skin Hydration Effectiveness of Plant-Based Moisturizers Smoo Buttergel and Smoo Baby Pure Moisturizing Lotion using Biophysical Methods and Comparison with Market Reference Products

Silphion Research Private Limited1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2025年8月11日最近更新:

试验速览

阶段
Phase 3 4
状态
尚未招募
发起方
入组人数
30
试验地点
1
主要终点
Increase in hydration level and duration of effect by each moisturiser using DermaLab Combo Hydration Probe

研究概览

简要总结

This study aims to provide valuable insights into the effectiveness, safety, and tolerability of plant-based moisturizers, with the goal of promoting more informed and healthier skincare choices. The main evaluation focus is the improvement in skin hydration and the duration of moisture retention after product application. Additional assessment parameters include product safety, user acceptability, and overall skin compatibility. The study evaluates two plant-based moisturizers, namely Smoo Buttergel and Smoo Baby Pure Moisturizing Lotion, against two well-known market reference products using biophysical measurement tools. Skin hydration is assessed using the DermaLab Combo Hydration Pin Probe, which measures skin conductance to reflect moisture levels. Each product is applied at 50 mg per 25 sq cm area, and hydration levels are recorded at multiple time points up to 24 hours post-application. This structured protocol allows for objective comparison of hydration performance across products. The findings are expected to enhance understanding of how plant-based moisturizers perform in comparison to conventional products, potentially benefiting public health by encouraging the use of gentler, more natural formulations.

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • Not on medication or medical care for 1 month before and during the study
  • Free from dermatological/systemic disorders affecting results
  • Available for the entire study duration
  • Provided written informed consent
  • Abstained from using soaps/moisturisers on test area for 1 week before and during study.

排除标准

  • Known sensitivity to cosmetics/moisturisers
  • Diagnosed with chronic skin allergies
  • Excessive hair on test sites
  • Pregnant or nursing women.

结局指标

主要结局

Increase in hydration level and duration of effect by each moisturiser using DermaLab Combo Hydration Probe

时间窗: 10 minutes, 1 hour, 4 hours, 6 hours, 24 hours

次要结局

  • Product safety, effectiveness, and tolerability(10 minutes, 1 hour, 4 hours, 6 hours, 24 hours)

研究者

发起方
Silphion Research Private Limited
申办方类型
Pharmaceutical industry-Indian
责任方
Principal Investigator
主要研究者

Ragavi

RENDER skin and hair

研究点 (1)

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