Can electronic cigarettes and nicotine replacement treatment help reduce smoking in smokers who struggle to quit?

Not Applicable

• Conditions: Smoking cessation; Mental and Behavioural Disorders

• Registration Number: ISRCTN13288677
• Lead Sponsor: Queen Mary University of London

Brief Summary

2021 results in https://pubmed.ncbi.nlm.nih.gov/34187081/ (added 06/07/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-03-23
• Study Completion: 2018-01-01
• Last Update Posted: 21 July 2021

Recruitment & Eligibility

• Sex: All
• Target Recruitment: 135

Inclusion Criteria

1. 18 years or older
2. Able to provide written informed consent
3. History of failed quit attempts using stop smoking medications and/or stop smoking services
4. Willing to use their allocated harm-reduction strategy for at least 4 weeks

Exclusion Criteria

1. Women who are pregnant or breastfeeding
2. Unable to read/write/understand English
3. Currently using EC or any stop smoking products
4. Taking part in other interventional research
5. Have a strong preference to use or not to use NRT or EC

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cigarette consumption per day, assessed by self-report in the follow up survey created for the purpose of the study at 1, 4 and 24 weeks post quit date/preparation date. Those who will report =50% smoking reduction will be validated with a CO reading in the clinic.

Secondary Outcome Measures

Name	Time	Method
<br> 1. Use of allocated harm reduction strategies<br> 2. Strategy ratings<br> 3. Changes in smoking behaviour<br> 4. Proportion of people still using allocated strategy at 6 months<br> All measured by the follow up survey created for the purpose of the study at 1, 4 and 24 weeks post quit date/preparation date<br>