DRKS00012877尚未招募2 期

Comparison of Response and Acute Toxicities of Concurrent Chemoradiation with Weekly Cisplatin Vs. Paclitaxel/Carboplatin in Locally Advanced Squamous Cell Carcinoma of Head & Neck: A Short-term Phase III Clinical Trial. - Shuayb HN CCRT Trial

Dr. Md Shuayb, MBBS, MSc, FCPS, Specialist, Oncology & Radiotherapy Centre, Square Hospitals Ltd.0 个研究点目标入组 100 人开始时间: 2017年8月16日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•1) SCCHN proved by histopathology.
•2) AJCC stage-III, IVA and IVB.
•3) Age: 18 to 75.
•4) Eastern Cooperative Oncology Group (ECOG) performance status = 2.
•5) Biochemical tests values: WBC= 3.5×10^9/L, Neutrophils =1.5×10^9/L, Platelets =100×10^9/L, haemoglobin =9gm/dl, Aspartate aminotransferase (AST), alanine aminotransferase (ALT), and total bilirubin =1.5×the upper limit of the institutional normal range, Creatinine concentration=120 umol/L, and creatinine clearance =50 ml/min.
•6) No serious diseases of important organs.
•7) Written informed consent signed prior to enrollment.

•1) Prior chemotherapy or head & neck irradiation,
•2) Pregnant or lactating woman,
•3) Serious diseases (include significant cardiovascular disease or uncontrolled diabetes) of important organs,
•4) Other malignancies,
•5) Active uncontrolled infection,
•6) Joined in other clinical trial,
•7) Stage IVB with cricoid cartilage invasion.

发起方

Dr. Md Shuayb, MBBS, MSc, FCPS, Specialist, Oncology & Radiotherapy Centre, Square Hospitals Ltd.