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临床试验/PACTR202002874953456
PACTR202002874953456已完成未知

on-penetrating deep sclerectomy versus trabeculectomy in primary congenital glaucoma

Faculty of Medicine0 个研究点目标入组 80 人开始时间: 2020年1月11日最近更新:

试验速览

阶段
未知
状态
已完成
发起方
入组人数
80

研究概览

简要总结

The current study was conducted on 80 eyes. Each of the NPDS and trabeculectomy groups included 40 eyes of 40 patients with the diagnosis of primary congenital glaucoma. The NPDS group mean age was 14.5 + 13.1 months versus mean age of 13.7 + 12.2 months in the trabeculectomy group. Males represented 60 % in the NPDS group and 65% in the trabeculectomy group. There was no statistically significant difference between the two groups regarding the demographic data of the included patients. At the end of the follow up period the mean IOP was 11.2 + 4.5 and 11.1 + 3.4 mmHg with a mean reduction of 16.2 and 17.4 mmHg in NPDS and trabeculectomy groups respectively. There was a statistically significant difference between preoperative and postoperative IOP levels along the whole follow up period for both groups (p < 0.001). At the end of the follow up period i.e. at 36 months postoperative, the complete success rate was 60 % (24 eyes) versus 57.5 % (23 eyes), the qualified success rate was 25 % (10 eyes) versus 25 % (10 eyes), the overall success rate was 85 % (34 eyes) versus 82.5 % (33 eyes), and the rate of failure was 15 % (6 eyes) versus 17.5 % (7 eyes) in NPDS and trabeculectomy groups respectively

研究设计

研究类型
Interventional

入排标准

年龄范围
1 Month(s) 至 23 Month(s)(—)
性别
All

入选标准

  • children presenting with primary congenital glaucoma under the age of 3 years

排除标准

  • Patients were excluded if they had secondary glaucoma i.e. only eyes with PCG were included,
  • or there was a coexisting ocular pathology e.g. congenital cataract
  • or a previous ocular surgery.
  • Patients with incomplete data or follow up period were also excluded.

研究者

发起方
Faculty of Medicine

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