NCT04363138已完成不适用
Link Between Eosinopenia and Bacterial Infections in the Elderly Subject Hospitalized in Geriatrics
Gérond'if1 个研究点 分布在 1 个国家目标入组 156 人开始时间: 2021年7月2日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 156
- 试验地点
- 1
- 主要终点
- Determine if eosinopenia is associated with bacterial infections by measuring eosinophil counts.
研究概览
简要总结
The main purpose of this monocentric, non-interventional, prospective study carried out in acute geriatrics (UGA) and post-rehabilitation care, is to determine if eosinopenia is associated with bacterial infections.
详细描述
It's a monocentric, non-interventional, prospective study carried.
At inclusion:
Non-opposition will be collected by the investigator upon entering the Geriatric Unit.
The investigators will have all the biological and radiological results and will decide whether or not to start antibiotic treatment.
Patients will be divided into 2 groups: group with bacterial infections and the other with non-bacterial diseases.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 75 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Hospitalized in Geriatrics.
- •First episode of:
- •Fever> 38 ° motivating the realization of a biological assessment.
- •Or Leukocytes> 10 g / l and C reactive protein (CRP) > 20 mg / l.
- •Be affiliated to a social security scheme.
- •No oral opposition to participation in the study and use of the data.
排除标准
- •Immunosuppression (HIV with CD4 <200 / mm3)
- •Active corticosteroid therapy
- •Chemotherapy, immunosuppressive treatment
- •Malignant hematological disease, lympho or myeloproliferative syndrome
- •Antibiotic therapy initiated before entering the geriatric ward
- •Documented parasitosis
- •Eosinophilic vasculitis
- •stroke <30 days
- •Patient already included in another study
- •Patient under guardianship or curatorship
- •Not affiliated with a social security scheme
- •Oral opposition to participation in the study
结局指标
主要结局
Determine if eosinopenia is associated with bacterial infections by measuring eosinophil counts.
时间窗: 1 month
次要结局
- Determine if the eosinophil counts (PNE) / neutrophil (PNN)x1000 < 4 ratio is associated with a bacterial infection by measuring this value.(1 month)
- Determine if eosinopenia is associated with mortality by measuring eosinophil counts.(1 month)
- Determine if deep eosinopenia is associated with bacterial involvement by measuring if this value is less than 10 per mm3.(1 month.)
- Determine if eosinopenia is associated with the effectiveness of antibiotics by measuring eosinophil counts.(1 month)
研究者
研究点 (1)
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