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临床试验/CTRI/2020/06/026145
CTRI/2020/06/026145尚未招募不适用

Incidence and risk factors of perioperative hypothermia in adults undergoing cancer surgery- A quality improvement audit

Tata Memorial Centre1 个研究点 分布在 1 个国家目标入组 2,000 人开始时间: 2020年6月28日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
2,000
试验地点
1
主要终点
To analyse the incidence of perioperative hypothermia in adult patients undergoing cancer surgery.

研究概览

简要总结

Anaesthesia (either general or neuraxial) is known to impair the thermoregulatory mechanisms that maintain the body temperature. As a result of this anaesthetised patients who are not warmed can become hypothermic with a temperature drop of 1- 2 °C. Hypothermia is defined as core body temperature < 36 ̊C. Hypothermia causes many pathophysiological changes like respiratory depression due to altered drug metabolism, increased oxygen demands, arrhythmias, myocardial ischaemia, tissue hypoxia, metabolic acidosis, and coagulopathy.Hypothermia is a silent and often missed factor with adverse post operative out- comes like delayed recovery, adverse cardiac events, increased risk of wound infection, delay in surgical site wound healing, increased transfusion requirements, patient discomfort due to shivering, prolonged ICU or hospital stay. Hence it is very important to maintain normothermia during the perioperative period.This study therefore aims to analyse incidence of perioperative hypothermia in cancer surgeries along with its risk factors and adverse effects like intra-operative arrhythmia, blood loss, delayed recovery from anaesthesia or neuromuscular blockade, unplanned post op ventilator support, post-op shivering, surgical site infection, prolonged ICU stay, prolonged hospital stay. We will also see if there are any complications like hyperthermia and thermal injury due to the warming measures.The results of this quality improvement audit would help in developing institution specific protocols for preventing perioperative hypothermia and improving patient care.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 99.00 Year(s)(—)
性别
All

入选标准

  • All surgeries lasting more than 30 mins.

排除标准

  • Emergency surgeries Day care procedures Patients needing therapeutic hypothermia.

结局指标

主要结局

To analyse the incidence of perioperative hypothermia in adult patients undergoing cancer surgery.

时间窗: 1. After induction of anaesthesia | 2. During the surgery hourly analysis | 3. Before shifting the patient out of the operation theatre | 4. Immediately after the surgery in the recovery room

次要结局

  • To identify the risk factors for perioperative hypothermia.(To observe incidence of adverse outcomes of perioperative hypothermia like intra operative arrhythmia, blood loss, delayed recovery from anaesthesia /neuromuscular blockade, unplanned post op ventilator support, post-op shivering, surgical site infection, prolonged ICU stay, prolonged hospital stay. The study will also observe if there are any complications like hyperthermia and thermal injury due to the warming measures.)

研究者

申办方类型
Research institution and hospital

研究点 (1)

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