ACTRN12610000615088CompletedPhase 2
The effects in critically ill patients of erythromycin when compared to placebo on small intestinal transit and nutrient absorption
Conditions
Trial Snapshot
- Phase
- Phase 2
- Status
- Completed
- Sponsor
- Adam Deane
- Enrollment
- 15
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
- Allocation
- Randomised controlled trial
- Primary Purpose
- Treatment
- Masking
- Blinded (masking used)
Eligibility Criteria
- Ages
- 18 Years to 90 Years (—)
- Sex
- All
Inclusion Criteria
- •Sedated and mechanically ventilated, critically ill patients Aged greater than 17 years, suitable for or receiving post-pyloric nutrition and likely to stay ventilated for at least 48 hours.
Exclusion Criteria
- •Pregnancy, Any contraindication to enteral feeding, Previous surgery on the oesophagus, stomach or duodenum, Any gastrointestinal surgery during their current hospital admission, Contraindication to moderate level of sedation or the use of an opiate for sedation and/or analgesia, Patients receiving erythromycin at an antimicrobial dose, Liver Dysfunction (defined as alanine a minotransferase (ALT) > 3 times the upper limit of normal)
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