Prospektive Evaluation of specimen quality for right sided colon cancer surgery
- Conditions
- C18Malignant neoplasm of colon
- Registration Number
- DRKS00012400
- Lead Sponsor
- Klinikverbund-suedwest
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 1373
Histologically proven adenocarcinoma of the colon - preoperative UICC stage I-III for scheduled surgery in curative intention
- Localisation coecum, ascending colon and hepatic flexure
- Pathologic stages UICC I-III
- Age >18 years
- Complete informed consent
- Colon Carcinomas distal to the hepatic flexure
- Multiple carcinomas
- Polyposis syndromes (FAP, Peutz-Jeghers S., Cronkhite-Canada S, Gardner S)
- other maligne conditions excluding basaliomas
- infammatory bowel disease (ulcerative colitis, Crohns disease, indeterminate colitis)
- emergency operations
- previous colon surgery
- impossible informed consent
- UICC stage IV
- previous Chemo- or Radiotherapy
- severes resepiratory or cardial insuffuciency, (NYHA IV), O2-Therapy
- terminal renal failure
- Liver failure (Bilirubin 1,5 mg %)
- Severe neurologic disorders
- Gravidity
- Contraindication against adjuvant Chemotherapy according to S3-guidelines
- HIV
- Hepatitis B/C
- persiting bacterial infection
- Rejection of data aquisition as required by the protocol
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 5 year disease free surviva. Assessment by contacting the General practitioner of the patients (yearly).
- Secondary Outcome Measures
Name Time Method 5 Year Overall-survival<br>postoperative morbidity and mortality