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Clinical Trials/NCT03739749
NCT03739749
Withdrawn
Not Applicable

Arthroscopic Superior Capsular Reconstruction - Multicentric Prospective Comparative Study of Different Types of Grafts

Hospital de Egas Moniz1 site in 1 countryOctober 30, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Rotator Cuff Tear
Sponsor
Hospital de Egas Moniz
Locations
1
Primary Endpoint
Constant score
Status
Withdrawn
Last Updated
3 years ago

Overview

Brief Summary

Multicentric prospective clinical and radiological comparative study of consecutive patients with irreparable rotator cuff tears to test the hypothesis that there are significant differences in the improvement of the clinical and imaging outcomes of arthroscopic superior capsular reconstruction (ASCR) when a different type of graft is used.

Detailed Description

Patients with irreparable rotator cuff tears who meet the eligibility criteria will be enrolled in the study and undergo arthroscopic superior capsular reconstruction using one of the following types of graft: fascia lata autograft, fascia lata allograft, Achilles tendon allograft, bovine pericardium xenograft, swine dermal xenograft, or collagen graft. All patients will be assessed clinically, radiologically and with an MRI preoperatively and at the 6-months and at the 2-years postoperative evaluations. The range of motion (ROM), shoulder abduction strength, Constant (CS), simple shoulder test (SST) and subjective shoulder value (SSV) scores will be compared from preoperative to 6 months postoperative; from 6 months postoperative to 2 years postoperative (paired-samples t-test, two-tailed) in each group (allotment to groups is performed according to the type of graft used: fascia lata autograft, fascia lata allograft, Achilles tendon allograft, bovine pericardium xenograft, swine dermal xenograft, or collagen graft). The differences in ROM, shoulder abduction strength, CS, SST and SSV scores from preoperative to 6 months postoperative and from 6 months postoperative to 2 years postoperative will be compared between groups. All continuous variables will be compared between the group of patients with graft tears and the group without graft tears (Mann-Whitney U test). All categorical variables and outcome results will be compared between groups (Fisher's exact test). A significant difference will be defined as P\<0.05.

Registry
clinicaltrials.gov
Start Date
October 30, 2018
End Date
October 30, 2022
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Hospital de Egas Moniz
Responsible Party
Principal Investigator
Principal Investigator

Clara Isabel de Campos Azevedo

Principal Investigator

Hospital de Egas Moniz

Eligibility Criteria

Inclusion Criteria

  • Rotator cuff tear arthropathy, Hamada stage 1 or 2
  • Complete rotator cuff tendon tear involving one or more tendons, with a Patte stage 3 tendon retraction on the preoperative magnetic resonance imaging

Exclusion Criteria

  • Rotator cuff tear arthropathy, Hamada stage 3 or 4
  • Complete rotator cuff tendon tear involving one or more tendons, with Patte stage 1 or 2 tendon retraction on the preoperative magnetic resonance imaging
  • Proximal humerus fracture
  • Acute shoulder dislocation (in the previous 8 weeks)

Outcomes

Primary Outcomes

Constant score

Time Frame: 2 years

Constant score at 2 years postoperatively (minimum 1 point - maximum 100 points); For the scale range provided, higher values represent a better outcome

Secondary Outcomes

  • Simple shoulder test(2 years)
  • Shoulder strength(2 years)
  • Graft integrity on the magnetic resonance imaging(2 years)
  • Shoulder active range of motion(2 years)
  • Acromiohumeral interval(2 years)

Study Sites (1)

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