NCT00498641CompletedPhase 3
Anisometropia Amblyopia Improved by Perceptual Learning and Patching
Conditions
Trial Snapshot
- Phase
- Phase 3
- Status
- Completed
- Sponsor
- Tri-Service General Hospital
- Primary Endpoint
- Corrected amblyopic logMAR visual acuity and contrast sensitivity function
Study Overview
Brief Summary
To compare the effects of perceptual learning with patching on improving visual acuity and contrast sensitivity in payient with anisometropic amblyopia.
Detailed Description
Patients with anisometropic amblyopia were randomized to patching or perceptual learning group. Corrected amblyopic logMAR visual acuity and contrast sensitivity function were measured at four-weekly intervals until visual acuity stabilized or amblyopia resolved. Improvement in visual acuity, contrast sensitivity, and the resolution of amblyopia were compared between groups.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Single
Eligibility Criteria
- Ages
- 3 Years to 55 Years (Child, Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Anisometropia without strabismus
- •An interocular acuity difference of at least 0.2 logMAR in children (3-7 years of age) or in older children and adult patients without a history of patching or atropine penalization
- •All patients wore their spectacle at least one year
Exclusion Criteria
- •A history of prior spectacle correction
- •A history of patching or optical penalization
- •The existence of an ocular disease that could contribute to decreased visual acuity
- •Learning difficulties
- •The presence of strabismus
Outcomes
Primary Outcomes
Corrected amblyopic logMAR visual acuity and contrast sensitivity function
Secondary Outcomes
No secondary outcomes reported
Investigators
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