COMPARATIVE CLINICAL STUDY OF AGNIKARMA AND VIRECHANA KARMA IN THE MANAGEMENT OF KARNINI YONIVYAPAD W.S.R. TO CERVICAL EROSION
- Conditions
- Erosion and ectropion of cervix uteri,
- Registration Number
- CTRI/2019/05/019010
- Lead Sponsor
- National Institute Of Ayurveda
- Brief Summary
In Ayurveda classics almost all of the gynaecological disorders are described under the heading of Yoni vyapad which are twenty in numbers. Karnini yonivyapad is one among them, the description of which seem to be near to Cervical erosion. Normally endocervix is covered by columnar epithelium and ectocervix is covered by squamous epithelium, but in erosion, it is replaced by columnar epithelium. Many of the times infection is the reason for the change in epithelial covering. But sometimes hormonal changes also play a pivotalrole in the changes of epithelial lining, patient suffers with offensive, irritent, profuse vaginal discharge, formation of nabothian folicle,contact bleeding,dyspareunia, intermenstrual bleeding, bowel irritating pelvic pain etc. If it is associated with cevicitis that leads to low back pain. It is also a cause of infertility and constitutional ill-health and sometimes it produces great psychological upset in women. If it is left untreated,in the chronic stages, the columnar epithelium undergoes squamous metaplasia. Its prevalence is more than 50 % of all the gyneacological conditions. In the present study two procedure are selected for comparison purpose in which first is Agnikarma. Second procedure is virechana karma. Acharya Charaka quoted that there is a chance of recurrence in disease treated by shaman therapy but Shodhan therapy cure the disease from its root and there is no chance of recurrence. For that Virchana karma has been selected as a Panchkarma procedure in present study. Virechana karma have been described in various samhitas for yonidosha and granthi chikitsa. there is a need of study to rule out the effective, safer, and economical methods of Doshas shodhna for the managment of cervical erosion. 30 patient suffering from Karnini Yonivyapad (cervical erosion) attending OPD and IPD section of NIA, Jaipur (Raj.) fulfill the inclusion criteria of the study will be randomly selected, irrespective of religion, occupation and soio-economic status. Patients will be randomly divided into two groups (15 patients In each groups). In group A Agnikarma with shalaka will be done in 15 patients and in group B Virechana karma with Trivrit lehya will be done in 15 patients.
Agnikarma procedure- The patient is in lithotomy position and the part is cleaned with aseptic solution and draping done. Speculum is to be introduced into the vagina and assessment of the cervical erosion done. Then cervix is to be cleaned. There after Agnikarma done by sterile pre heated shalaka instrument applied to the eroded part of cervix.the sign of Samyaka Dagdha is the Kapota/Talaphalavata and bluish brown colour will be marked.
Virechana karma- First of all Deepana, Pachana, With Panchkol churna (3gm) twice a day before food till appearance of Nirama lakshana. snehpana with Go ghrita till Samyaka snigdha lakshana. Than Virechana karma will be induced by Trivrit lehya. Virechana karma followed by Samsarjana karmaas per the type of Shuddhi.
Trial Drugs- 1.Deepana- Pachana- Panchkola churna(A.H.SU.6/166) 2.Drugs for Virechana karma-Trivrit Lehya (AFI vol.-I Part A Page no. 163-164) (A.H.Kalp 2/9)
colposcopywill be used as the objective parameter. folloe up will be done after 7 days of treatment which will be carried out for 1 month. Assessment will be done on the basis of objective and subjective parameter before treatment, after treatment, and during last follow up. Appropriate statistical test will be applied.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Female
- Target Recruitment
- 30
- A) Clinically diagnosed patients of cervical erosion (Karnini) on per speculum examination, irrespective of symptoms.
- B) Married women irrespective of parity.
- C) Age between 20 to 45 years.
- A) Pregnant women having cervical erosion B) Women of age less than 20 and more than 45 years C) Positive patients of Human Immunodeficiency Virus, VDRL and HBs Ag D) Patients with Intra Uterine Contraceptive Device insertion or on Oral contraceptive pills.
- E) Any organic pathology of reproductive tract like endometrial cancer, cervical cancer, cervical intraepithelial neoplasia.
- F) Patient having severe systemic disorders like Diabetes, Hypertension, Tuberculosis etc.
- G) Patients with Menorrhagia, Metrorrhagia and Polymenorrhoea.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical evaluation of efficacy of Virechna karma in the management of karnini (cervical erosion) and to compare the clinical efficacy of Agnikarma with Virechna Karma in Karnini yonivyapad (Cervical erosion). evaluation of efficacy of Virechna karma in the management of karnini (cervical erosion).
- Secondary Outcome Measures
Name Time Method To evaluate clinical efficacy of Virechna karma procedure by using Trivrit Lehya in karnini (Cervical erosion) evaluate clinical efficacy of Virechna karma procedure by using Trivrit Lehya in karnini (Cervical erosion)
Trial Locations
- Locations (1)
National Institute Of Ayurveda Jaipur
🇮🇳Jaipur, RAJASTHAN, India
National Institute Of Ayurveda Jaipur🇮🇳Jaipur, RAJASTHAN, IndiaDr Richa TiwariPrincipal investigator09414583139richa.ayurved@gmail.com