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Clinical Trials/NCT07283003
NCT07283003
Recruiting
Not Applicable

Prospective Randomized Study on the Necessity of Postoperative Stenting After Ureteroscopy (URS) for Ureteral Stones.

Lukas J Hefermehl1 site in 1 country60 target enrollmentStarted: January 8, 2026Last updated:

Overview

Phase
Not Applicable
Status
Recruiting
Sponsor
Lukas J Hefermehl
Enrollment
60
Locations
1
Primary Endpoint
Postoperative pain assessment

Overview

Brief Summary

Comparison of routine postoperative stenting versus no stenting after ureterorenoscopy for ureteral stones to assess the necessity and impact on complication risk.

Detailed Description

After a ureteroscopy (URS) for the removal of ureteral stones, a double-J stent is routinely placed. Among other measures, this is intended to prevent pain caused by ureteral swelling, small residual fragments, blood clots, and potential drainage obstructions, which could lead to colic or fever. However, the evidence supporting the benefit of this practice is limited. At the same time, many patients report discomfort due to the stent (e.g., flank pain, dysuria, frequent urination, hematuria), which can significantly impact their quality of life.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Age 18 years or older
  • Patients with ureteral stones scheduled for ureteroscopy (URS) and stone removal
  • Previous pre-stenting
  • Informed Consent as documented

Exclusion Criteria

  • Complex ureteral conditions (e.g., known ureteral strictures)
  • Impacted stones
  • Solitary kidney
  • Patients with significant renal stones (\>3mm)
  • Previous ureteral surgeries (except endoscopic stone treatments)
  • Pregnancy or suspected pregnancy

Arms & Interventions

No-Stent Group

Active Comparator

No postoperative double-J catheter following ureterorenoscopy.

Intervention: No Double-J catheter insertion (Other)

Stent Group

Active Comparator

Routine postoperative double-J catheter insertion following ureterorenoscopy.

Intervention: Double-J catheter (Procedure)

Outcomes

Primary Outcomes

Postoperative pain assessment

Time Frame: up to 4 weeks postoperative

Assessment of postoperative pain will be conducted using the Visual Analogue Scale (VAS) and the study-specific mobile application HEATMAP (Byldr GmbH, Switzerland). The primary outcome is the difference between the pain scores recorded by the VAS and those recorded by the HEATMAP application at predefined postoperative time points \[both measured on a scale from 1-10, with higher scores indicating greater pain\].

Secondary Outcomes

  • Length of stay [days](During the hospital stay, on average 2 days)
  • Pain Assessment(pre-/peri-/postoperative)
  • Pain Management(pre-/peri-/postoperative)
  • Secondary need of double-J catheter(up to 4 weeks postoperative)
  • Procedure related readmissions(up to 4 weeks postoperative)
  • Procedure related reoperations(up to 4 weeks postoperative)
  • Comprehensive Complication Index(up to 4 weeks postoperative)

Investigators

Sponsor
Lukas J Hefermehl
Sponsor Class
Other
Responsible Party
Sponsor Investigator
Principal Investigator

Lukas J Hefermehl

Principal Investigator

Kantonsspital Baden

Study Sites (1)

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