NCT00894621Unknown4 期
Norepinephrine as Early Vasopressor Therapy in Children Undergoing Mechanical Ventilation
Unidade de Terapia Intensiva1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2008年11月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- To compare norepinephrine and placebo as initial therapy in pediatric patients submitted to the mechanical ventilation with reference to hemodynamic parameters, diuresis and diuretics' use.
研究概览
简要总结
The purpose of this study is to assess the effectiveness from early infusion of norepinephrine in pediatric patients submitted to mechanical ventilation for the use of sedative and analgesics drugs.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 1 Month 至 12 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children, who, in the arrival or during the admission in pediatric intensive care unit, develop the need for mechanical ventilation and continuous infusion of sedatives and/or analgesics
排除标准
- •Patients after cardiac arrest
- •Patients with tracheostomy
- •Patients with renal and/or hepatic failure
- •Patients with previous episode of cardiac arrythmia
- •Patients with mechanical ventilation forecast lesser that four days
研究组 & 干预措施
Norepinephrine
Experimental
干预措施: Norepinephrine (Drug)
Placebo
Placebo Comparator
干预措施: Placebo (Drug)
结局指标
主要结局
To compare norepinephrine and placebo as initial therapy in pediatric patients submitted to the mechanical ventilation with reference to hemodynamic parameters, diuresis and diuretics' use.
时间窗: 5 days
次要结局
- To assess possible side effects related with the early norepinephrine infusion.(5 days)
研究者
研究点 (1)
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