Effects of Transcranial Direct Current Stimulation (tDCS) in Chronic Corneal Pain

Not Applicable

Completed

• Conditions: Neuropathic Pain; Corneal Pain; Chronic Pain
• Interventions: Device: Transcranial Direct Current Stimulation (tDCS)

• Registration Number: NCT01575002
• Lead Sponsor: Spaulding Rehabilitation Hospital

Brief Summary

In this study the investigators aim to examine the effects of Transcranial Direct Current Stimulation (tDCS) on pain levels as well as the changes in cognitive (thought) processing in individuals with chronic pain of the cornea -- and also compared with healthy controls.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-01
• Study First Submitted: 2012-02-08
• Study First Submitted QC: 2012-04-09
• Study First Posted: 2012-04-10
• Primary Completion: 2015-09
• Study Completion: 2015-09
• Status Verified: 2020-04
• Last Update Submitted: 2020-04-23
• Last Update Posted: 2020-04-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 26

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Active tDCS	Transcranial Direct Current Stimulation (tDCS)	Subjects will undergo 20 minutes of active tDCS stimulation.
Sham tDCS	Transcranial Direct Current Stimulation (tDCS)	Subjects will undergo 20 minutes of sham tDCS stimulation.

Primary Outcome Measures

Name	Time	Method
Changes in pain scales	Measured for approximately 2 weeks	We will measure changes in the visual analogue scale (VAS) for pain, and also measure pain threshold (using an algometer) before and after each stimulation session. We will compare the measurements from before stimulation to after stimulation, in each scheduled session, as this study is measuring the effects of a single session of tDCS.

Secondary Outcome Measures

Name	Time	Method
Changes in EEG measurements	Measured for approximately 2 weeks	We will measure changes in event related potentials (ex. P300, mismatch negativity) recorded via electroencephalography (EEG) before and after each stimulation session. We will compare the measurements from before stimulation to after stimulation, in each scheduled session, as this study is measuring the effects of a single session of tDCS.

Trial Locations

Locations (1)

Spaulding Rehabilitation Hospital; 🇺🇸 Boston, Massachusetts, United States