NL-OMON53775RecruitingNot Applicable
ongitudinal MRI study to catch EARLY scoliotic changes of the Bone and Intervertebral Disc in younger sisters and daughters of adolescent idiopathic scoliosis patients and in boys and girls of the 22q11.2DS population. - Earlybird
niversitair Medisch Centrum Utrecht0 sites120 target enrollmentStarted: TBDLast updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- Enrollment
- 120
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 2 to 11 (—)
Inclusion Criteria
- •- 8, 9 or 10 years old
- •- An older sibling, twin or parent diagnosed with AIS
- •- No clinical signs of scoliosis at inclusion (physical examination by forward
- •bending test and Bunnell Scoliometer assessment with a cut-off value of 7°.
- •- Written informed consent of parents/legal representatives.
- •- Diagnosed with 22q11.2DS
- •- Girls: 8, 9 or 10 years old.
- •- Boys: 9, 10 or 11 years old.
- •- No clinical signs of scoliosis at inclusion (physical examination by forward
- •bending test and Bunnell Scoliometer assessment with a cut-off value of 7°.
- •- Written informed consent of parents/legal representatives.
Exclusion Criteria
- •Contraindications for MR imaging
- •Early-onset scoliosis or other spinal deformities
- •Other syndromes or neuromuscular disease associated with scoliosis
- •Clinical signs of >1cm leg length discrepancy
- •Other diseases or injuries, that are related to abnormal spinal growth,
- •posture, activity levels, or scoliosis development.
Investigators
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