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Post-market Clinical Follow-up Study of Alcon PRECISION1™ Spherical and PRECISION1™ for Astigmatism Soft Contact Lenses

Conditions
Refractive Errors
Interventions
Device: Verofilcon A spherical soft contact lenses
Device: Verofilcon A toric soft contact lenses
Registration Number
NCT06462456
Lead Sponsor
Alcon Research
Brief Summary

The purpose of this study is to assess long term performance and safety of verofilcon A soft contact lenses in a real-world setting in a population of 7 years or older having at least 1 year of verofilcon A (sphere or toric) contact lens wear in a daily wear and daily disposable modality.

Detailed Description

This study consists of a Baseline Visit and a Year 1 Visit.

The Baseline Visit is defined as the first office visit where an eye care professional provided an in-person office biomicroscopy exam to the subject before or during which a PRECISION1™ sphere or toric contact lens prescription was released. The Baseline Visit will be retrospective, with all assessments obtained from chart review.

The Year 1 Visit is defined as the visit that occurs 1 year (-2/+4 months) since Baseline during which period the subject is wearing test lenses of the same design in both eyes and a contact lens examination is performed during the visit. The Year 1 Visit may be prospective or retrospective.

Recruitment & Eligibility

Status
ENROLLING_BY_INVITATION
Sex
All
Target Recruitment
168
Inclusion Criteria
  • Subject (or subject's legal representative) is able to understand and sign an informed consent/assent form approved by an Institutional Review Board (IRB), unless appropriate consent waiver for the retrospective chart review is provided by the IRB.
  • Verofilcon A (sphere or toric) contact lens wear as described in the protocol.
  • Best corrected spectacle distance visual acuity (VA) 20/25 or better at baseline.
  • Healthy, non-diseased eyes, as determined/known by the Investigator.
  • Other protocol-defined inclusion criteria may apply.

Key

Exclusion Criteria
  • Any ocular disease or condition that would contraindicate contact lens wear present at baseline.
  • Use of systemic or ocular medications that would contraindicate contact lens wear at baseline.
  • Other protocol-defined exclusion criteria may apply.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
PRECISION1 SphereVerofilcon A spherical soft contact lensesVerofilcon A spherical soft contact lenses worn in both eyes in a real-world setting
PRECISION1 ToricVerofilcon A toric soft contact lensesVerofilcon A toric soft contact lenses worn in both eyes in a real-world setting
Primary Outcome Measures
NameTimeMethod
Incidence of Microbial KeratitisUp to Year 1

Microbial keratitis is a sight-threatening infection of the cornea.

Distance Visual Acuity with Study Lenses at Year 1 Follow-UpYear 1

Visual acuity (VA) assessed per the investigator's standard of care with study lenses in place.

Distance Visual Acuity with Study Lenses at BaselineBaseline

Visual acuity (VA) assessed per the investigator's standard of care with study lenses in place.

Incidence of Corneal Infiltrative EventsUp to Year 1

A corneal infiltrate is a single or group of inflammatory cells in the normally clear cornea.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (12)

Scripps Optometric Group

🇺🇸

San Diego, California, United States

Pearle Vision

🇺🇸

Jacksonville, Florida, United States

Vision Health Institute

🇺🇸

Orlando, Florida, United States

Vision Salon Eye Care Associates

🇺🇸

Blue Island, Illinois, United States

Illinois College of Optometry

🇺🇸

Chicago, Illinois, United States

CORL, Indiana University

🇺🇸

Bloomington, Indiana, United States

The Eye Doctors Inc

🇺🇸

Eden Prairie, Minnesota, United States

Cornea and Contact Lens Institute of Minnesota

🇺🇸

Edina, Minnesota, United States

Complete Eye Care of Medina

🇺🇸

Medina, Minnesota, United States

Spectrum Eyecare

🇺🇸

Jamestown, New York, United States

Eyecare Professionals, Inc

🇺🇸

Powell, Ohio, United States

Optometry Group, PLLC

🇺🇸

Memphis, Tennessee, United States

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