NCT02081313已完成不适用
Syndrome de Netherton : Aspects Cliniques, Physiopathologiques et Identification de Cibles thérapeutiques
Institut National de la Santé Et de la Recherche Médicale, France2 个研究点 分布在 1 个国家目标入组 18 人开始时间: 2014年10月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 18
- 试验地点
- 2
- 主要终点
- Measurement of seric cytokines levels
研究概览
简要总结
This study aims at studying the natural history of Netherton syndrome (NS), to identify the consequences of LEKTI deficiency on the immune system and to characterize new molecular mechanisms involved in the disease.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adult or child (no age limit)
- •Confirmed diagnosis of Netherton syndrome
- •Signed informed consent form for the patient or his legal representative
排除标准
- •Bleeding disorder precluding skin biopsy
结局指标
主要结局
Measurement of seric cytokines levels
时间窗: 3 months after patient recruitment
次要结局
- Pattern of skin abnormalities(3 months after patient recruitment)
研究者
研究点 (2)
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