Differential effects of active versus passive occupational therapy on the excitability of the motor cortex in stroke patients

Not Applicable

• Conditions: Cerebral infarction; I60; I62; I61; I63; I64; Subarachnoid haemorrhage; Intracerebral haemorrhage; Other nontraumatic intracranial haemorrhage; Stroke, not specified as haemorrhage or infarction

• Registration Number: DRKS00033842
• Lead Sponsor: urija Institut Kliniken Schmieder Allensbach

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-03-07
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

1. Ability to give informed consent to participate in the study
2. Sufficient understanding of the task
3. No or minor pain in the affected arm, measured by visual analog scale
4. First stroke (ischemia or hemorrhage), not longer than 6 months ago
5. Rehabilitation phase C or D
6. Paresis of the upper extremity with a strength level of 3 to 4

Exclusion Criteria

1. Cognitive impairments that do not allow information about the study (e.g. Wernicke's aphasia, global aphasia, dementia)
2. Warticipants with a lack of compliance
3. Pain
4. Participants with electronic implants (e.g. pacemakers)
5. Epilepsy
6. Pregnancy
7. Intracranial metal particles (e.g. vascular clips)

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Transcranial magnetic stimulation: single stimulus amplitudes, short- and longlatency intracortical inhibition, intracortical facilitation, cortical silent periode

Secondary Outcome Measures

Name	Time	Method
Box-and-block test