NL-OMON56275CompletedNot Applicable
Effect of monomeric and oligomeric flavanols on exercise blood pressure and vascular function in healthy volunteers - Effect of monomeric and oligomeric flavanols on exercise blood pressure
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- niversiteit Maastricht
- Enrollment
- 41
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 18 to 64 (—)
Inclusion Criteria
- •1. Healthy men and women with normal to high-normal resting blood pressure
- •(systolic blood pressure (SBP) 120 - 139 mm Hg and diastolic blood pressure 80
- •- 89 mm Hg).
- •2. Age 35 - 65 years
- •3. BMI 20 - 32 kg/m^2
- •4. Hypertensive response to maximal exercise test defined as SBP >= 200 mm Hg
- •(men) and >= 180 mm Hg (women).
Exclusion Criteria
- •1. Active engagement in the weight loss programs, also including slimming
- •2. Active smoking or abstinence from smoking for less than one year.
- •3. Use of medications that reduce BP and/or can potentially influence other
- •study outcomes (ACE-inhibitors, angiotensin receptor blockers, diuretics,
- •painkillers, etc).
- •4. Intake of polyphenol-containing supplements for two month before and during
- •the whole course of the study.
- •5. History of diabetes, cardiovascular, respiratory, renal, gastrointestinal,
- •hepatic or other diseases and conditions, which potentially can compromise
- •participation in this study.
- •6. Intense sporting (>10 h/week) and/or participation in the competition at the
- •professional level.
- •7. Pregnancy or breastfeeding.
- •8. Participation in a clinical trial within four weeks prior to inclusion into
- •this study.
- •9. Vaccination against Covid-19 within two months before the
- •screening/randomization visit or expected vaccination against Covid-19 during
Investigators
Similar Trials
Completed
Not Applicable
se of monomeric and oligomeric flavanols in the dietary management of patients with type 2 diabetes and microalbuminuriaDiabetes type 2, microalbuminuriaNL-OMON20416Erasmus Medical Center, Department of Internal Medicine96
Completed
Not Applicable
se of monomeric and oligomeric flavanols in the dietary management of patients with type 2 diabetes and microalbuminuriakidney protein leakage in diabetesMicroalbuminuria in diabetes type 210012653NL-OMON46959Erasmus MC, Universitair Medisch Centrum Rotterdam114
Completed
Not Applicable
Effect of MOF on Exercise Blood PressureHealthyNCT04907097Maastricht University Medical Center40
Completed
Not Applicable
A pharmacokinetic study of flavonoids derived from foodJPRN-UMIN000043413Morishita Jintan Co.,Ltd.5
Completed
Not Applicable
Effects of micronised purified flavonoic fraction on microcirculation in women suffering from chronic venous diseaseChronic venous diseaseCirculatory SystemOther disorders of veinsISRCTN18841175Institut de Recherches Internationales Servier (France)240