Ocular measures for detection of driving impairment due to sleep loss, alcohol and benzodiazepine use

Phase 4

Completed

• Conditions: sleep- and drug-related motor vehicle accident risk; healthy volunteers; Injuries and Accidents - Other injuries and accidents; Public Health - Health promotion/education

• Registration Number: ACTRN12609000289213
• Lead Sponsor: Austin Health

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-05-18
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

healthy, drivers licence, alcohol intake in standard drinks >0 average <5/day for males and < 3/day for females

Exclusion Criteria

1.Epilepsy
2.Diabetes requiring insulin
3.Chronic psychiatric illness
4.Visual impairment which does not correct with glasses
5.Unable to speak and read English
6.Drink more than 5 caffeinated beverages per day
7.Significant daytime sleepiness (Epworth Sleepiness Scale score > 11).
8.Chronic neurological illness
9.Chronic liver disease, diabetes requiring insulin or renal impairment
10.Pregnancy or breast feeding
11.Sleep apnoea, narcolepsy
12.Use of sedating medication
13.Anticoagulation with warfarin

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ocular measures tested by Optalert: slow eyelid closure, blink amplitude, saccades, EOG[baseline, following intervention during each session]

Secondary Outcome Measures

Name	Time	Method
driving performance using the AusEd driving simulator: lane position variability[baseline, following intervention in each session]