Effect of Action Observation and Motor Imagery Therapy on Balance, Functional Status and Quality of Life in Stroke, Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 56
- 试验地点
- 2
- 主要终点
- The difference in the scores of the Brunnstrom stages between pre- and post-rehabilitation assessments
研究概览
简要总结
In recent years, motor imagery (MI) and action observation (AO) therapy strategies have been used in rehabilitation programs to increase motor learning in stroke. Visuomotor training strategies such as AO and MI therapy rely on the activity of the mirror neuron system to facilitate motor re-learning. Mirror neurons are activated during the performance of goal-directed actions, also when observing the same action and visualizing the action in the mind.
This clinical trial aims to test whether the application of AO and MI treatment in stroke in addition to conventional rehabilitation programs has an additional effect on motor recovery, activities of daily living, and quality of life.
详细描述
Stroke is one of the most common neurological disorders that causes chronic disability in adulthood. Stroke-related neurological dysfunction causes impairment in motor and sensory skills and limitation in the ability to perform daily living activities, resulting in decreased independence of patients. This process causes significant impairment in the quality of life of stroke patients.
In recent years, motor imagery (MI) and action observation (AO) therapy strategies have been used in rehabilitation programs to increase motor learning in stroke. Visuomotor training strategies such as AO and MI therapy rely on the activity of the mirror neuron system to facilitate motor re-learning. Mirror neurons are activated during the performance of goal-directed actions, also when observing the same action and visualizing the action in the mind.
This clinical trial aims to test whether the application of AO and MI treatment in stroke in addition to conventional rehabilitation programs has an additional effect on motor recovery, activities of daily living, and quality of life.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
盲法说明
Single
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who had a stroke in the last year
- •Functional Ambulation Classification score 2-5
排除标准
- •Patients who have had repeated strokes
- •Patients with neglect
- •Patients with cognitive dysfunction (those who cannot follow simple verbal instructions)
- •Patients with severe hearing problems
- •Patients with severe vision problems
- •Patients with additional musculoskeletal system pathology that will affect physical performance (such as amputation, severe joint mobility limitation, peripheral nerve damage)
- •Patients with uncontrolled hypertension and diabetes mellitus
- •Patients with a history of symptomatic lung disease (such as asthma, chronic obstructive pulmonary disease, emphysema)
- •Patients with a history of symptomatic cardiac disease (such as coronary artery disease, arrhythmia, heart failure)
- •Patients with peripheral artery disease
研究组 & 干预措施
Sham action observation and motor imagery therapy for rehabilitation
Sham comparator for action observation and motor imagery therapy for rehabilitation in stroke patients in addition to conventional rehabilitation programs.
干预措施: Sham action observation and motor imagery therapy for rehabilitation (Other)
Action observation and motor imagery therapy for rehabilitation
Action observation and motor imagery therapy for rehabilitation in stroke patients in addition to conventional rehabilitation programs.
干预措施: Action observation and motor imagery therapy for rehabilitation (Other)
结局指标
主要结局
The difference in the scores of the Brunnstrom stages between pre- and post-rehabilitation assessments
时间窗: 6 weeks
Univariate statistical analyses will be performed to calculate differences in the scores of the Brunnstron stages between pre- and post-rehabilitation assessments. Brunnstrom staging assesses the motor recovery process of the hemiplegic patient in 6 stages (Stages 1 to 6). Upper extremity, lower extremity, and hand are evaluated separately. Higher stages indicate better motor function.
The difference in the scores of the Fugl-Meyer Assessment between pre- and post-rehabilitation assessments
时间窗: 6 weeks
Univariate statistical analyses will be performed to calculate differences in the scores of the Fugl-Meyer Assessment between pre- and post-rehabilitation assessments. The Fugl-Meyer Assessment is a stroke-specific, performance-based impairment index. It is designed to assess motor functioning, balance, sensation and joint functioning in patients with post-stroke hemiplegia. The motor domain is used in this study, which includes items assessing movement, coordination, and reflex action of the upper and lower extremities. Motor score ranges from 0 (hemiplegia) to 100 points (normal motor performance). Divided into 66 points for upper extremity and 34 points for the lower extremity.
次要结局
- The difference in the scores of the Barthel Index between pre- and post-rehabilitation assessments(6 weeks)
- The difference in the scores of the Stroke-Specific Quality of Life Scale between pre- and post-rehabilitation(6 weeks)
研究者
Yurdagül Bahran Muştu
M.D., Principal investigator
Karamanoğlu Mehmetbey University