sing Two Different Cut-Off Levels of Fecal Immunochemical Test in the High-Risk and Non-High-Risk Subjects to Maintain the High-Rate Detection of Advanced Colorectal Neoplasia: A Population-Based Colorectal Cancer Screening in Thailand

In summary, the 5 micrograms per gram FIT cutoff for high-risk subjects and 20 micrograms per gram FIT cutoff for non-high-risk subjects reducing the need in healthcare resources, navigating those who really need for colonoscopy but still balancing the comparable detection of advanced adenoma and CRC. This personalized FIT-based approach is promising for CRC screening in resource-constrained countries. Further research is required to assess its long-term impact on CRC incidence and mortality.