CTRI/2023/07/055349Not yet recruitingPhase 4
Comparative evaluation of effects ofclopidogrel versus prasugrel in combination with aspirin as dual antiplatelet therapy on inflammatory and oxidative stress parameters in patients with acute coronary syndrome. A randomized, open-label, parallel-group study. - NI
Trial Snapshot
- Phase
- Phase 4
- Status
- Not yet recruiting
- Sponsor
- Pt B D Sharma PGIMS Rohtak
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
Inclusion Criteria
- •18â??65-year-old patients of either sex with acute coronary syndrome (ACS) as diagnosed by a cardiologist. Patients eligible for dual antiplatelet treatment on the basis of cardiovascular risk category and American college of cardiology/American heart association guidelines
- •(ACC/AHA).Patients willing to participate in the study and give informed consent.
Exclusion Criteria
- •Patients who are already on any antiplatelet drug.
- •Patients having contraindications to the use of any study drug.
- •Present or past history of active bleeding.
- •Pregnant and lactating women, inadequate contraception.
- •Patients with known inflammatory/infective diseases.
- •Patients with severe extra cardiac diseases limiting life expectancy.
- •Known renal dysfunction (serum creatinine >=1.8 mg/dL in women, >=2.0 mg/dL in men).
- •Known hepatic impairment (aspartate aminotransferase, alanine aminotransferase >3 times upper limit of normal).
Investigators
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