Cardiovascular autonomic function and metabolomic profile in chronic obstructive pulmonary disease

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Cardiovascular autonomic function in chronic obstructive pulmonary disease (COPD) patients with all stages
Sponsor: Faculty of Medicine Siriraj Hospital, Mahidol University
Enrollment: 88
Last Updated: last year

No summary available.

Registry

who.int

Start Date

May 19, 2022

End Date

May 19, 2023

Last Updated

last year

Study Type

Observational

Sex

All

Sponsor

•COPD patients, all severity (mild, moderate, severe and very severe), as defined by the Global Initiative for Obstructive Lung Disease (GOLD) guidelines (2\) with forced expiratory volume in 1 second (FEV1\)/forced vital capacity (FVC) ratio \< 0\.7 will be recruited if they meet the following criteria:
•1\) Age between 40\-80 years old;
•2\) Stable conditions, i.e. no acute exacerbation, change in pharmacological therapy, or hospital admission in the past 1 month;
•3\) Good ability to communicate and follow instructions.

•Subjects of either group will be excluded from this study if they meet the following criteria:
•1\) History of diabetes mellitus, cardiac arrhythmias, lung cancer, or mental disorder;
•2\) Alcoholism and/or current smoker;
•3\) Musculoskeletal or neurological abnormalities, such as stroke, upper limb or lower limb injuries;
•4\) Acute conditions, such as fever, uncontrolled hypertension.