Time-dependent effects of green tea on pharmacokinetics of nadolol in healthy volunteers
Not Applicable
- Conditions
- Healthy volunteers
- Registration Number
- JPRN-UMIN000019398
- Lead Sponsor
- Fukushima Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 11
Inclusion Criteria
Not provided
Exclusion Criteria
Smoker
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Blood samples are collected before and at 0.5, 1, 2, 3, 4, 6, 8, 24,and 48 hours after nadolol administration. Urine samples are obtained over 48 hours after nadolol administration. Blood pressure and pulse rate are monitored before and at 0.5, 1, 2, 3, 4, 6, 8, 24, and 48 hours after nadolol adoministration.
- Secondary Outcome Measures
Name Time Method Plasma concentrations of nadolol Urinary excretions of nadolol Blood pressure Pulse rate