Ten-year Outcomes After AF Ablation

Completed

• Conditions: Atrial Fibrillation

• Registration Number: NCT01867099
• Lead Sponsor: Valley Health System

Brief Summary

Ablation of atrial fibrillation (AF) using pulmonary vein isolation is employed when patients do not respond favorably to medical therapy. Successful procedures are accomplished in the majority of patients, but the outcome after many years of follow-up after ablation is unknown.

Detailed Description

A prospectively identified cohort of 445 patients who demonstrated freedom from AF for at least one year following ablation (single procedure in 391, 87.9%) was followed for 66.0 ± 34.0 months. Patients were seen at least annually as outpatients, and underwent regular ECG monitoring, especially if there were symptoms suggestive of recurrent arrhythmia. Continued absence of arrhythmia was defined as freedom from AF or flutter \> 30 secs.

Study Timeline

• Study Start: 2002-12
• Primary Completion: 2012-12
• Study Completion: 2012-12
• Study First Submitted: 2013-05-29
• Study First Submitted QC: 2013-05-29
• Study First Posted: 2013-06-03
• Status Verified: 2014-12
• Last Update Submitted: 2014-12-13
• Last Update Posted: 2014-12-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 445

Inclusion Criteria

• Prior AF ablation procedure
• No AF for one year post ablation

Exclusion Criteria

• Geographic inaccessibility
• Longstanding persistent AF
• Recurrent AF within one year of ablation
• Prior AF ablation

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Atrial fibrillation or flutter > 30 secs	More than one year after successful primary ablation or redo procedure within 6 mos

Trial Locations

Locations (1)

Valley Hospital; 🇺🇸 Ridgewood, New Jersey, United States