Long-term Outcome After Initially Successful Catheter Ablation of Atrial Fibrillation by Pulmonary Vein Isolation: a Ten-Year Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 445
- 试验地点
- 1
- 主要终点
- Atrial fibrillation or flutter > 30 secs
研究概览
简要总结
Ablation of atrial fibrillation (AF) using pulmonary vein isolation is employed when patients do not respond favorably to medical therapy. Successful procedures are accomplished in the majority of patients, but the outcome after many years of follow-up after ablation is unknown.
详细描述
A prospectively identified cohort of 445 patients who demonstrated freedom from AF for at least one year following ablation (single procedure in 391, 87.9%) was followed for 66.0 ± 34.0 months. Patients were seen at least annually as outpatients, and underwent regular ECG monitoring, especially if there were symptoms suggestive of recurrent arrhythmia. Continued absence of arrhythmia was defined as freedom from AF or flutter > 30 secs.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Prior AF ablation procedure
- •No AF for one year post ablation
排除标准
- •Geographic inaccessibility
- •Longstanding persistent AF
- •Recurrent AF within one year of ablation
- •Prior AF ablation
结局指标
主要结局
Atrial fibrillation or flutter > 30 secs
时间窗: More than one year after successful primary ablation or redo procedure within 6 mos
次要结局
未报告次要终点
研究者
Jonathan Steinberg,MD
Director, Arrhythmia Institute
Valley Health System