跳至主要内容
临床试验/NCT03534908
NCT03534908Unknown不适用

Nonalcoholic Fatty Liver Disease and Cardiovascular Disease: the Correlation Analysis and Risk Prediction Model Study

Wuhan University1 个研究点 分布在 1 个国家目标入组 5,000,000 人开始时间: 2017年9月25日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
5,000,000
试验地点
1
主要终点
the prevalence of NAFLD in China

研究概览

简要总结

Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in the world. NAFLD is associated with a lot of comorbidity, such as diabetes, metabolic syndrome, coronary heart disease and chronic kidney diseases. However, the correlation between the NAFLD and cardiovascular disease (CVD) events remains controversial. This study is an observational study based on a big retrospective cohort in china to explore the prevalence of NAFLD in China, the risk factors associated with NAFLD, as well as whether patients with NAFLD are more prone to experience CVDs and CVD events.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • males or females aged 18-75

排除标准

  • malignancy except primary liver cancer
  • pregnancy or breastfeeding
  • liver diseases of other etiology including hepatitis C virus infection ,autoimmune hepatitis,Wilson's disease,hemachromatosis,drug-induced hepatitis,parenteral nutrition
  • excessive alcohol consumption
  • cases missing crucial data

结局指标

主要结局

the prevalence of NAFLD in China

时间窗: June,2020

次要结局

  • to indicate the prevalence of CVDs and CVD events in people with and without NAFLD(October,2020)
  • the risk factors associated with NAFLD(August,2020)

研究者

发起方
Wuhan University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Hongliang Li

MD,PhD

Wuhan University

研究点 (1)

Loading locations...

相似试验

Nonalcoholic Fatty Liver Disease and Cardiovascular... | 临床试验