NCT03534908Unknown不适用
Nonalcoholic Fatty Liver Disease and Cardiovascular Disease: the Correlation Analysis and Risk Prediction Model Study
Wuhan University1 个研究点 分布在 1 个国家目标入组 5,000,000 人开始时间: 2017年9月25日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 5,000,000
- 试验地点
- 1
- 主要终点
- the prevalence of NAFLD in China
研究概览
简要总结
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in the world. NAFLD is associated with a lot of comorbidity, such as diabetes, metabolic syndrome, coronary heart disease and chronic kidney diseases. However, the correlation between the NAFLD and cardiovascular disease (CVD) events remains controversial. This study is an observational study based on a big retrospective cohort in china to explore the prevalence of NAFLD in China, the risk factors associated with NAFLD, as well as whether patients with NAFLD are more prone to experience CVDs and CVD events.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 75 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •males or females aged 18-75
排除标准
- •malignancy except primary liver cancer
- •pregnancy or breastfeeding
- •liver diseases of other etiology including hepatitis C virus infection ,autoimmune hepatitis,Wilson's disease,hemachromatosis,drug-induced hepatitis,parenteral nutrition
- •excessive alcohol consumption
- •cases missing crucial data
结局指标
主要结局
the prevalence of NAFLD in China
时间窗: June,2020
次要结局
- to indicate the prevalence of CVDs and CVD events in people with and without NAFLD(October,2020)
- the risk factors associated with NAFLD(August,2020)
研究者
Hongliang Li
MD,PhD
Wuhan University
研究点 (1)
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