Nonalcoholic Fatty Liver Disease and Cardiovascular Disease: the Correlation Analysis and Risk Prediction Model Study
- Conditions
- NAFLDCardiovascular Diseases
- Registration Number
- NCT03534908
- Lead Sponsor
- Wuhan University
- Brief Summary
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in the world. NAFLD is associated with a lot of comorbidity, such as diabetes, metabolic syndrome, coronary heart disease and chronic kidney diseases. However, the correlation between the NAFLD and cardiovascular disease (CVD) events remains controversial. This study is an observational study based on a big retrospective cohort in china to explore the prevalence of NAFLD in China, the risk factors associated with NAFLD, as well as whether patients with NAFLD are more prone to experience CVDs and CVD events.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 5000000
Inclusion Criteria
- males or females aged 18-75
Exclusion Criteria
- malignancy except primary liver cancer
- pregnancy or breastfeeding
- liver diseases of other etiology including hepatitis C virus infection ,autoimmune hepatitis,Wilson's disease,hemachromatosis,drug-induced hepatitis,parenteral nutrition
- excessive alcohol consumption
- cases missing crucial data
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method the prevalence of NAFLD in China June，2020
- Secondary Outcome Measures
Name Time Method to indicate the prevalence of CVDs and CVD events in people with and without NAFLD October，2020 the risk factors associated with NAFLD August，2020
Trial Locations
- Locations (1)
Wuhan University
🇨🇳Wuhan, Hubei, China