comparison of modified thoracoabdominal plane nerve block through perichondrial approach and subcostal transversus abdomens plane block for quality of post operative analgesia in patients undergoing laparoscopic cholecystectomy a randomised controlled trial
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Median numeric pain rating score NRS in first 24 hours post operatively between thoracoabdominal nerve block and subcostal transversus abdominis block groups .
研究概览
简要总结
Now a days laparoscopic cholecystectomy is a procedure of choice in surgical treatment for
symptomatic cholelithiasis Recovery after laparoscopic cholecystectomy depends upon
several factors Such as abdominal pain nausea vomiting and fatigue Although post
operative pain after laparoscopic cholecystectomy mainly depends upon factors like
peritoneal stretching and diaphragmatic irritation caused by high intraabdominal pressure and
by carbon dioxide retention Nonetheless total abdominal pain following laparoscopic
cholecystectomy is having somatic and visceral components Therefore our aim should be
to reduce the somatic component of pain that is incisional pain after laparoscopic
cholecystectomy It has also been stated that laparoscopic cholecystectomy causes significant
postoperative pain in one third of post operative patients up to first 24 hours after surgery A
recent PROSPECT review reported that standard way to reduce postoperative pain after
laparoscopic cholecystectomy is preoperative or intraoperative use of paracetamol with
NSAID and port site Local anaesthetic infiltration with long acting local anaesthetic agent
and also suggests that there is no role of number of surgical port insertion recently
published review and meta-analysis suggest that subcostal transversus abdominis plane
TAP block is having greatest reduction in pain score at 12 hours postoperatively compared
with other regional analgesic techniques
Subcostal TAP block was first suggested by Hebbard et al. and it is proven to provide
adequate analgesia for upper and lower abdominal surgeries However, pain from the
incision site for the right lateral port in the laparoscopic cholecystectomy may not be
covered because it cannot block the lateral cutaneous branches of the thoracoabdominal
nerves To compensate this shortcomings of subcostal TAP block, Tulgar et al. introduced a
newer regional analgesic technique called as modified thoracoabdominal nerve block
through the perichondral approach M TAPA in 2019 In this technique local anesthetics
are administered only to the underside of the perichondrial surface of tenth rib It has been
found that this technique provides a sensory block between T5-T12 dermatomes This has
recently been used for postoperative analgesia in laparoscopic abdominal surgeries because it
is considered to provide effective analgesia in the anterior and lateral thoracoabdominal
wallsThere are limited literature comparing the efficacy of modified thoracoabdominal nerve blocks M TAPA with
subcostal transversus abdominis plane blocks STAP therefore further studies are required to conclude the efficacy between the two fascial plane block
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant, Investigator, Outcome Assessor and Date-entry Operator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)(—)
- 性别
- All
入选标准
- •American Society of Anesthesiologists (ASA) classes I–II patients Patients 18 yrs to 65yrs of age Planned for laparoscopic cholecystectomy of either sex under general anaesthesia.
排除标准
- •ASA III-IV patients Any known drug allergies Contraindication to nerve block like coagulopathy bleeding diathesis and local infections Not giving the consent for the block Inability to understand or use the numerical rating scale and QOR 15 score.
结局指标
主要结局
Median numeric pain rating score NRS in first 24 hours post operatively between thoracoabdominal nerve block and subcostal transversus abdominis block groups .
时间窗: At 0 min 15 min 30 min 1 hour 3 hour 6 hour 12 hour 24hours postoperative
次要结局
- 1Mean dose in mg opioid consumption in morphine equivalent mgperkg in first 24 hours postoperatively(2 Mean duration of analgesia in minutes)
研究者
Sania
lady hardinge medical college and associated hospitals
