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Clinical Trials/NCT04386096
NCT04386096
Completed
Not Applicable

Randomized Controlled Trial of Web Based Tools to Improve Medication Continuity in Adolescents With ADHD

Children's Hospital Medical Center, Cincinnati1 site in 1 country40 target enrollmentJune 1, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Attention Deficit Hyperactivity Disorder
Sponsor
Children's Hospital Medical Center, Cincinnati
Enrollment
40
Locations
1
Primary Endpoint
Proportion of Days Covered With Medicine
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

Medication is an efficacious treatment strategy for adolescents with attention-deficit/hyperactivity disorder (ADHD), however use significantly declines during adolescence when the consequences of ADHD are most severe (e.g. dropping out of school, delinquency, etc.). The Unified Theory of Behavior Change (UTBC) has been proposed as a conceptual model to explain the mechanism underlying ADHD medication adherence and to guide the development of interventions to improve the continuity of treatment. The UTBC is a well-established and empirically tested model that identifies factors that influence an individual's intention to perform a behavior as well as factors that influence whether a behavior is actually carried out. Indeed, the research team's preliminary data support the relevance of pre-intention factors and implementation factors for medication continuity among adolescents with ADHD. Currently, no evidence-based interventions target medication continuity for adolescents with ADHD. The objective of this study is to test a multi-component intervention that systematically identifies and targets aspects of the UTBC model most relevant for each adolescent with poor ADHD medication continuity. The central hypothesis is that the tailored intervention will support ADHD medication continuity. The study will objectively test the central hypothesis by conducting a randomized controlled trial among adolescents with poor medication continuity to test whether the intervention engages the mechanism underlying medication continuity and improves outcomes.

Registry
clinicaltrials.gov
Start Date
June 1, 2020
End Date
May 24, 2021
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • First prescribed ADHD medicine more than one year prior to enrollment
  • Treated by pediatrician at practice participating in study
  • Filled at least one prescription for a stimulant medication in the past year

Exclusion Criteria

  • More than 80% of days covered with medicine over past one year
  • Poor understanding level: The participant and parent cannot understand or follow instructions given in the study.
  • Do not have reliable access to the internet at their home or another location.
  • Parent will not permit their child to access the internet for study related activities
  • Are not able or willing to send or receive text messages for study related activities

Outcomes

Primary Outcomes

Proportion of Days Covered With Medicine

Time Frame: An average of 4 months

This will be calculated based pharmacy dispensing records

Secondary Outcomes

  • Change in Intention to Take/Give ADHD Medicine Regularly(At baseline and approximately 4 months later)
  • Fidelity to Intended Use of Intervention Components(An average of 4 months)
  • Change in Pre-intention Factors of Unified Theory of Behavior Change(At baseline and approximately 4 months later)
  • Change in Medication Diversion(At baseline and approximately 4 months later)
  • Change in Adolescent-report of Medication Barriers(At baseline and approximately 4 months later)
  • Change in Parent-report of Medication Barriers(At baseline and approximately 4 months later)
  • Change in Decision Making Involvement Scale(At baseline and approximately 4 months later)

Study Sites (1)

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