Volume of 0.5% ropivacaine needed to produce anaesthesia of upper limb in 50% of patients using ultrasound guided multiple injection lateral sagittal infraclavicular plexsus block
Phase 4
- Conditions
- Health Condition 1: O- Medical and SurgicalHealth Condition 2: M968- Other intraoperative and postprocedural complications and disorders of musculoskeletal system, not elsewhere classified
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients with American Society of Anesthesiologists (ASA) physical status I-II patients, in the age group of 18-60 years, with a body mass index (BMI) between 18 and 30 kg.m-2, scheduled to undergo forearm and hand surgeries will be assessed for eligibility
Exclusion Criteria
Patients with local infection at the block site, coagulopathy, sepsis, BMI >30, allergy to local anesthetics, uncontrolled hypertension or ischemic heart disease, renal or hepatic dysfunction, pre-existing neurological deficits, prior surgery in the infraclavicular fossa, psychiatric illness, patients who failed to understand the scoring systems used in the study and patients who refused to give consent for the study will be excluded.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary objective will be to estimate MEV90 for multiple-injection US-guided ICB. Volume assignment will be carried out using a biased coin design (BCD) up-and-down sequential method (UDM), where the volume administered to each patient will depend upon the response of previous patient. First subject will receive 21 ml based upon a previous study MEV50 of 19 ml in patients receiving ultrasound-guided LSIB with ropivacaine 7.5 mg/ml. based on the response of the previous patient. In case of failure, the next subject will receive a higher volume (0.5ml/ cord). If the previous patient had a successful block, the next subject will be randomized to a lower volumeTimepoint: 30 minutes after performance of block
- Secondary Outcome Measures
Name Time Method Time to requirement of first bolus, mean pain scores at various time intervalsTimepoint: Baseline ie on shifting to PACU, 2hrs, 4hrs , 8hrs, 12hrs, 24hrs