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CoCo-20: a Longitudinal Follow-up Study of the French Paediatric Population During and After the Coronavirus Pandemic COVID-19

Completed
Conditions
Mental Health Disorder
Interventions
Diagnostic Test: Quantitative and qualitative assessments of mental health
Registration Number
NCT04498416
Lead Sponsor
Fondation Lenval
Brief Summary

In the context of a viral outbreak and of widespread quarantine measures, a significant increase in psychological disorders, such as stress or fear behaviours, had previously been observed. This distress has been described on adults, but no data have been collected yet for paediatric populations.

After a traumatic event, children and adolescents may present several clinical consequences, the most common being Post-Traumatic Stress Disorder (PTSD). Moreover, PTSD in children and adolescents is often associated with comorbid disorders, such Attention Deficit Hyperactivity Disorder, depression, attachment and anxiety disorders, sleep disturbances and behavior problems.

The aim of this study is to present the methodology of "CoCo 20" : is to assess the impact of the pandemic of coronavirus disease 2019 (Covid-19) and of seclusion measures on mental health and on the development of psychological disorders in children in the short to medium term

Detailed Description

In the context of a viral outbreak and of widespread quarantine measures, a significant increase in psychological disorders, such as stress or fear behaviours, had previously been observed. This distress has been described on adults, but no data have been collected yet for paediatric populations.

After a traumatic event, children and adolescents may present several clinical consequences, the most common being Post-Traumatic Stress Disorder (PTSD). Moreover, PTSD in children and adolescents is often associated with comorbid disorders, such Attention Deficit Hyperactivity Disorder, depression, attachment and anxiety disorders, sleep disturbances and behavior problems.

The aim of this study is to present the methodology of "CoCo 20" : is to assess the impact of the pandemic of coronavirus disease (Covid-19) and of seclusion measures on mental health and on the development of psychological disorders in children in the short to medium term.

The major inclusion criteria are children and adolescents under 18 years of age who have been affected by the Covid 19 pandemic. Three groups were defined: children in group one had a previous history of traumatic events, those in group two had a record of previous psychiatric or psychological disorder with a follow-up treatment and Group three included children without traumatic history nor psychiatric or psychological follow-up treatment. Participants will be assessed at baseline (V0), 1 week after (V1), one month after baseline (V2), one week after the end of the containment (V3) and one month after the end of the containment (V4).

Main analyses comprise analyses of variance and regression analyses of predictors of clinical evolution over time

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
70
Inclusion Criteria
  • Children affected by the Coronavirus disease 2019 (Covid-19) pandemic;
  • Age between 0 and under 18 at the time of inclusion;
  • Affiliated with a social security scheme;
  • Having a good command of the French language (French);
  • Children whose parents have accepted participation in the study (collection of informed consents).
Exclusion Criteria
  • Children and/or young adults with a psychotic disorder or autism spectrum disorder;
  • Children and/or young adults with an average intellectual disability (< to 50);
  • Person deprived of liberty by judicial or administrative decision1;
  • Person subject to a period of exclusion for another search.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Group 3 ControlQuantitative and qualitative assessments of mental healthchildren without traumatic experience and without psychiatric or psychological follow-up treatment.
Group 1 Post-Traumatic Stress Disorder (PTSD)Quantitative and qualitative assessments of mental healthchildren with an identified traumatic history
Group 2 PathologyQuantitative and qualitative assessments of mental healthchildren with psychological follow-up treatment for a psychiatric disorder, without traumatic history;
Primary Outcome Measures
NameTimeMethod
diagnosis of possible psychological and psychiatric difficulties at baselineat baseline Day 0

measure of psychological and psychiatric difficulties in connection with the pandemic and confinement. This will allow a rapid implementation of a course of care adapted and specific to the difficulties presented by each child, by Quantitative and qualitative assessments :

Secondary Outcome Measures
NameTimeMethod
follow up of psychological and psychiatric difficulties at V2at one month after baseline

measure of psychological and psychiatric difficulties in connection with the pandemic and confinement. This will allow a rapid implementation of a course of care adapted and specific to the difficulties presented by each child, by Quantitative and qualitative assessments

follow up of psychological and psychiatric difficulties at V3at one week after the end of the containment

measure of psychological and psychiatric difficulties in connection with the pandemic and confinement. This will allow a rapid implementation of a course of care adapted and specific to the difficulties presented by each child, by Quantitative and qualitative assessments

follow up of psychological and psychiatric difficulties at V4at one month after the end of the containment

measure of psychological and psychiatric difficulties in connection with the pandemic and confinement. This will allow a rapid implementation of a course of care adapted and specific to the difficulties presented by each child, by Quantitative and qualitative assessments

impact of traumatic history prior to confinementat one week after baseline and at one month after the end of the containment

measure by Post-Traumatic Stress Disorder (PTSD) scale: The frequency and intensity of PTSD symptoms will be assessed using the Young Child PTSD Checklist (YCP) for children aged 3 months to 6 years and 11 months; or the Child PTSD checklist (CPC) for children aged 7 years to 17 years and 11 months ; or with the Post-Traumatic Stress Disorder ( PTSD) checklist 5 (PCL 5 ) for adults

impact of other previous psychiatric disordersat one month after baseline and at one month after the end of the containment

measure by Kiddie Schedule for Affective Disorders and Schizophrenia (K-SADS): This is a semi-directed interview for children over the age of 7. It is done by interviewing the parent and the child. The interview covers both current issues.

parental reactionat one week after baseline and at one week after the end of the containment

measure by Parenting stress index-short form (PSI-SF) that measures the extent of parental stress, as well as stress in the relationship between parent and child, and parents' difficulties in the day-to-day management of children.

Trial Locations

Locations (1)

Hôpitaux Pédiatriques de Nice CHU-Lenval

🇫🇷

Nice, France

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