NCT00315666CompletedPhase 3
Prophylactic Effect of Memantine in Chronic Tension-Type Headache
Conditions
Drugs
Trial Snapshot
- Phase
- Phase 3
- Status
- Completed
- Sponsor
- Danish Headache Center
- Enrollment
- 40
- Locations
- 2
- Primary Endpoint
- Headache duration
Study Overview
Brief Summary
The purpose of this study is to test whether memantine has a prophylactic effect on chronic tension-type headaches.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Treatment
- Masking
- Double
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Chronic tension-type headache
- •Normal urine pH
Exclusion Criteria
- •More than 1 migraine attack/month
- •Other major illnesses
- •Overuse of medicine/alcohol
- •Women not using AC
- •Pregnant/breast-feeding women
- •Allergy to memantine
Outcomes
Primary Outcomes
Headache duration
Headache intensity
Secondary Outcomes
- Side effects
- Headache frequency
- The use of simple analgesics
Investigators
Study Sites (2)
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