Magnetoencephalography by Optical Pumping Magnetometer
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 70
- 试验地点
- 2
- 主要终点
- Signal to noise ratio of the MEG OPM
研究概览
简要总结
MagnetoEncephaloGraphy (MEG) is a method of recording brain activity with high temporal resolution and good spatial resolution, compared to current recording techniques such as ElectroEncephaloGraphy (EEG). The main limitation of MEG is its cost due to the sensors used, the Super Quantum Interference Devices (SQUID). These require a complex infrastructure from an instrumentation point of view to operate, requiring liquid helium, most often at a loss, at increasing cost. Optical Pumping Magnetometers (OPM) type sensors represent a promising alternative to SQUIDs sensors, especially since they do not require helium cooling.
The purpose of this project is to Identify biomarkers in Magnetoencephalography of normal brain development in healthy adults, premature and term newborns from "a priori" obtained by the classical technique of High Resolution EEG performed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 1 Day 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •For healthy adult volunteers
- •Age between 18 and 65
- •No pathology, no treatment
- •No toxicant intake
- •For term newborns
- •Child between 38 and 42 weeks gestational age on the day of registration
- •No pathology, no treatment
- •For children born prematurely
- •Child between 28 and 36 weeks gestational age on the day of registration
- •No pathology, no treatment apart from routine care related to prematurity
- •For pregnant women
- •Pregnant with between 28 to 40 weeks gestational age on the day of registration
- •No pathology, no treatment
排除标准
- •Subject and Patients "not compatible" MEG. Wearers of prosthesis or pacemaker likely to generate artefacts interfering with the measurement. There is no danger to the subject, but the measurement itself may be impossible.
- •Patients who cannot stand to stand still for a few minutes.
- •Newborn on ventilatory assistance or infusion
- •Newborn baby not meeting the age criteria
结局指标
主要结局
Signal to noise ratio of the MEG OPM
时间窗: 1 day
Signal to noise ratio of the MEG OPM is in dB
Signal to noise ratio of HR EEG
时间窗: 1 day
Signal to noise ratio of HR EEG is in dB
Number of dB between Signal to noise ratio of the MEG OPM and Signal to noise ratio of HR EEG
时间窗: 1 day
次要结局
未报告次要终点