Magnetoencephalography by Optical Pumping Magnetometer
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Magnetoencephalography
- Sponsor
- Centre Hospitalier Universitaire, Amiens
- Enrollment
- 70
- Locations
- 1
- Primary Endpoint
- Signal to noise ratio of the MEG OPM
- Status
- Recruiting
- Last Updated
- 11 months ago
Overview
Brief Summary
MagnetoEncephaloGraphy (MEG) is a method of recording brain activity with high temporal resolution and good spatial resolution, compared to current recording techniques such as ElectroEncephaloGraphy (EEG). The main limitation of MEG is its cost due to the sensors used, the Super Quantum Interference Devices (SQUID). These require a complex infrastructure from an instrumentation point of view to operate, requiring liquid helium, most often at a loss, at increasing cost. Optical Pumping Magnetometers (OPM) type sensors represent a promising alternative to SQUIDs sensors, especially since they do not require helium cooling.
The purpose of this project is to Identify biomarkers in Magnetoencephalography of normal brain development in healthy adults, premature and term newborns from "a priori" obtained by the classical technique of High Resolution EEG performed.
Investigators
Eligibility Criteria
Inclusion Criteria
- •For healthy adult volunteers
- •Age between 18 and 65
- •No pathology, no treatment
- •No toxicant intake
- •For term newborns
- •Child between 38 and 42 weeks gestational age on the day of registration
- •No pathology, no treatment
- •For children born prematurely
- •Child between 28 and 36 weeks gestational age on the day of registration
- •No pathology, no treatment apart from routine care related to prematurity
Exclusion Criteria
- •Subject and Patients "not compatible" MEG. Wearers of prosthesis or pacemaker likely to generate artefacts interfering with the measurement. There is no danger to the subject, but the measurement itself may be impossible.
- •Patients who cannot stand to stand still for a few minutes.
- •Newborn on ventilatory assistance or infusion
- •Newborn baby not meeting the age criteria
Outcomes
Primary Outcomes
Signal to noise ratio of the MEG OPM
Time Frame: 1 day
Signal to noise ratio of the MEG OPM is in dB
Signal to noise ratio of HR EEG
Time Frame: 1 day
Signal to noise ratio of HR EEG is in dB
Number of dB between Signal to noise ratio of the MEG OPM and Signal to noise ratio of HR EEG
Time Frame: 1 day