Long Term Results of Combined Transpupillary Thermotherapy (TTT) Indocyanine Green (ICG) Based Photodynamic Therapy (PDT) in Choroidal Melanoma
- Conditions
- Choroidal Melanoma
- Interventions
- Procedure: TTT + ICG-based PDT
- Registration Number
- NCT01253759
- Lead Sponsor
- New England Retina Associates
- Brief Summary
This is a report of 10 years results of combined Transpupillary thermotherapy (TTT) treatment with Indocyanine green (ICG) in controlling small and medium-sized choroidal melanomas.
- Detailed Description
The study was done in a Clinical practice setting. Forty six eyes of 46 patients with small or medium-sized choroidal melanomas were treated with i-TTT using infrared light delivered from a diode laser. All patients were evaluated to rule out systemic metastasis and underwent a complete ophthalmological evaluation including: Slit lamp biomicroscopy, dilated fundus examination, Fluorescein angiography, Optical coherence tomography and A/B ultrasonography. Main outcome measures were: Changes in visual acuity, complications associated with the treatment and local control of the tumor.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 46
- Small and medium-sized choroidal melanoma
- Patients older than 18 years old.
- Patients who can read and signed the informed consent.
- Patients with ocular inflammation.
- Patients with another active ocular disease.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description 1 TTT + ICG-based PDT Combined treatment of Transpupillary Thermotherapy and ICG-based photodynamic therapy (PDT)
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
New England Retina Associates
🇺🇸Hamden, Connecticut, United States