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临床试验/NCT03140917
NCT03140917已完成不适用

Multimodal Assessment of Liver Volume and Function in Patients With Colorectal Liver Metastases

Karolinska University Hospital1 个研究点 分布在 1 个国家目标入组 10 人开始时间: 2016年4月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
10
试验地点
1
主要终点
Correlation between HBS and MRI in assessment of FLR function preop

研究概览

简要总结

In liver surgery peroperative assessment och the future liver remnant (FLR) is pivotal in order to avoid posthepatectomy liver failure. To date this is mainly performed by measuring the volume of the FLR. Of course FLR volume acts as a surrogate measure of FLR function and the correlation between volume and function is not always accurate. Several techniques to assess FLR function has been proposed. Hepatobiliary scintigraphy (HBS) and Dynamic MRI are the two such methods. In this study we compare HBS and MRI, in addition to contrast-enhanced CT and ICG, repeatedly performed before and after right hepatectomy in patients with colorectal liver metastases treated with neoadjuvant chemotherapy.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • CRLM treated with neoadjuvant chemotherapy subjected to right hepatectomy

排除标准

  • 未提供

结局指标

主要结局

Correlation between HBS and MRI in assessment of FLR function preop

时间窗: Preop

HBS, MRI, CT and ICG performed the day before surgery

次要结局

  • Correlation between HBS and MRI in assessment of FLR function POD 7(POD 7)
  • Correlation between HBS and MRI in assessment of FLR function POD 28(POD 28)

研究者

发起方
Karolinska University Hospital
申办方类型
Other
责任方
Principal Investigator
主要研究者

Ernesto Sparrelid

MD PhD

Karolinska University Hospital

研究点 (1)

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