Multimodal Assessment of Liver Volume and Function in Patients With Colorectal Liver Metastases
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Correlation between HBS and MRI in assessment of FLR function preop
研究概览
简要总结
In liver surgery peroperative assessment och the future liver remnant (FLR) is pivotal in order to avoid posthepatectomy liver failure. To date this is mainly performed by measuring the volume of the FLR. Of course FLR volume acts as a surrogate measure of FLR function and the correlation between volume and function is not always accurate. Several techniques to assess FLR function has been proposed. Hepatobiliary scintigraphy (HBS) and Dynamic MRI are the two such methods. In this study we compare HBS and MRI, in addition to contrast-enhanced CT and ICG, repeatedly performed before and after right hepatectomy in patients with colorectal liver metastases treated with neoadjuvant chemotherapy.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •CRLM treated with neoadjuvant chemotherapy subjected to right hepatectomy
排除标准
- 未提供
结局指标
主要结局
Correlation between HBS and MRI in assessment of FLR function preop
时间窗: Preop
HBS, MRI, CT and ICG performed the day before surgery
次要结局
- Correlation between HBS and MRI in assessment of FLR function POD 7(POD 7)
- Correlation between HBS and MRI in assessment of FLR function POD 28(POD 28)
研究者
Ernesto Sparrelid
MD PhD
Karolinska University Hospital
