A comparative study between Dexmedetomidine and Clonidine as adjuvant with Ropivacaine in ultrasound guided erector spinae block for post operative analgesia in modified radical mastectomy.

Summary:

Breast cancer surgeries are increasingly performed but adequate postoperative analgesia is often

not achieved leading to complications and worsened quality of life. Erector Spinae Plane Block

using ropivacaine has emerged as a promising regional anaesthesia technique that can

effectively control pain and offers lesser complications than their alternate available modalities.

Alpha2 adrenergic agonists like clonidine and dexmedetomidine are used as adjuvants in peripheral

nerve blocks to increase the duration of analgesia for effective control of pain. Very few studies

have been done to compare their efficacy in ESPB. Hence this study is proposed to explore their

differences.

OBJECTIVE OF PROPOSED RESEARCH

To compare the duration of analgesia between dexmedetomidine and clonidine as an adjuvant in

ultrasound guided Erector Spinae Plane Block using Ropivacaine.

METHODOLOGY

After getting approval of the Institutional Ethics Committee, patient recruitment will be done.

Selection of patients base on the inclusion and exclusion criteria will be followed by proper

counselling and informed consent will be taken. Patients will be divided by sequential sampling in

either of two groups, RC and RD; according to the adjuvant clonidine or dexmedetomidine use.

Preoperative US-guided ESPB will be done and in the postoperative period the duration of

analgesia, level of sedation and hemodynamic parameters will be measured.

EXPECTED OUTCOME

At the end of this study, we will find out if there is any significant difference between

dexmedetomidine and clonidine in their ability to increase the duration of analgesia when used as an

adjunct to ropivacaine in erector spinae plane block.