Cardiovascular Outcome Study to Evaluate the Effect of Obicetrapib in Patients With Cardiovascular Disease

Phase 3

Active, not recruiting

• Conditions: Atherosclerotic Cardiovascular Disease
• Interventions: Drug: Placebo; Drug: Obicetrapib

• Registration Number: NCT05202509
• Lead Sponsor: NewAmsterdam Pharma

Brief Summary

This study will be a placebo-controlled, double-blind, randomized, phase 3 study in participants with Atherosclerotic Cardiovascular Disease (ASCVD) who are not adequately controlled despite maximally tolerated lipid-lowering therapy.

Detailed Description

This study will be a placebo-controlled, double-blind, randomized, phase 3 study to evaluate the effect of 10mg Obicetrapib in participants with Atherosclerotic Cardiovascular Disease (ASCVD) who are not adequately controlled despite maximally tolerated lipid-lowering therapy to reduce the risk of cardiovascular death, myocardial infarction, stroke and non-elective coronary revascularization. The PREVAIL Study

Study Timeline

• Study First Submitted: 2021-11-22
• Study First Submitted QC: 2022-01-20
• Study First Posted: 2022-01-21
• Study Start: 2022-02-07
• Status Verified: 2024-06
• Last Update Submitted: 2024-06-03
• Last Update Posted: 2024-06-04
• Primary Completion: 2026-11
• Study Completion: 2026-11

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 9541

Inclusion Criteria

• Males & females ≥ 18 years age.
• Established ASCVD including:
• Coronary artery disease
• Cerebrovascular disease
• Peripheral Artery disease
• On maximally tolerated lipid-modifying therapy
• Fasting LDL-C ≥ 55 mg/dL
• Fasting triglycerides < 400 mg/dL
• Estimated glomerular filtration rate ≥ 30 mL/min

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Exclusion Criteria

• New York Heart Association class III or IV heart failure or left ventricular ejection fraction < 30%
• Have been hospitalized for Heart Failure within 5 years prior to screening
• Had non-fatal MI, non-fatal stroke, non-elective coronary revascularization and/or hospitalization for unstable angina or chest pain within past 3 months prior to screening
• Uncontrolled hypertension
• Diagnosis of homozygous familial hypercholesterolemia (HoFH)
• Active liver disease
• HbA1c ≥10%
• Thyroid Stimulating Hormone (TSH) > 1.5 times upper limit normal
• Creatine kinase > 3 times upper limit normal
• History of malignancy with surgery in past 3 years
• History of alcohol or drug abuse within past 5 years
• Received treatment with investigational product or device within past 30 days excluding Coronavirus treatment or vaccine
• Known allergy to study drug
• Participated in previous obicetrapib trial
• Taking gemfibrozil within 30 days screening

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Placebo	Placebo	one placebo tablet, once daily
obicetrapib 10mg	Obicetrapib	one 10mg tablet, once daily.

Primary Outcome Measures

Name	Time	Method
Major Adverse Cardiovascular Effect (MACE)	30 months after last participant randomized	To evaluate the effect of obicetrapib on the risk of MACE

Trial Locations

Locations (589)

Northwest Heart Clinical research; 🇺🇸 Arlington Heights, Illinois, United States

Eclipse Clinical Research; 🇺🇸 Tucson, Arizona, United States

NEA Baptist clinic; 🇺🇸 Jonesboro, Arkansas, United States

Advanced Research Center; 🇺🇸 Anaheim, California, United States

Amicis Research; 🇺🇸 Northridge, California, United States

Valley Clinical Trials, Inc; 🇺🇸 Northridge, California, United States

Lundquist Institute for Biomedical Innovation at Harbor UCLA Medical Center; 🇺🇸 Torrance, California, United States

Excel Medical Clinical Trials; 🇺🇸 Boca Raton, Florida, United States

Clearwater Cardiovascular and Interventional Consultants; 🇺🇸 Clearwater, Florida, United States

Avail Clinical Research; 🇺🇸 DeLand, Florida, United States

ActivMed Practices and Research - Methuen; 🇺🇸 Methuen, Massachusetts, United States

St. Louis Heart and Vascular Cardiology; 🇺🇸 Saint Louis, Missouri, United States

Mid-Hudson Medical Research, PLLC - New Windsor; 🇺🇸 New Windsor, New York, United States

IMA Clinical Research PC and Affiliates- New York, NY; 🇺🇸 New York, New York, United States

Cary Research Group, LLC; 🇺🇸 Cary, North Carolina, United States

The Presbyterian Hospital DBA Novant Health Heart and Vascular Institute; 🇺🇸 Charlotte, North Carolina, United States

Moses H. Cone Memorial Hospital Operating Corporation d/b/a Cone Health; 🇺🇸 Greensboro, North Carolina, United States

Clinical Trials of America, LLC - Lenoir, NC; 🇺🇸 Lenoir, North Carolina, United States

Pinehurst Medical Clinic, Inc.; 🇺🇸 Pinehurst, North Carolina, United States

Piedmont Healthcare - Statesville; 🇺🇸 Statesville, North Carolina, United States

Nowe Zdrowie-Ck Kieltucki i Wspolnicy Spolka Jawna; 🇵🇱 Staszów, Poland

Lynn Institute of Norman; 🇺🇸 Norman, Oklahoma, United States

Penn State Health Medical Group- Berks Cardiology; 🇺🇸 Wyomissing, Pennsylvania, United States

South Texas Research Institute; 🇺🇸 Edinburg, Texas, United States

Mt. Olympus Medical Research; 🇺🇸 Friendswood, Texas, United States

Linq Research, LLC; 🇺🇸 Pearland, Texas, United States

Sherman Clinical Research; 🇺🇸 Sherman, Texas, United States

Stephenville Medical & Surgical Clinic; 🇺🇸 Stephenville, Texas, United States

Prevea Health; 🇺🇸 Green Bay, Wisconsin, United States

Western Health; 🇦🇺 Saint Albans, Australia

The Queen Elizabeth Hospital (TQEH) - SA Health; 🇦🇺 Woodville South, Australia

Dr Heart Pty Ltd at Cholesterol Care Australia; 🇦🇺 Woolloongabba, Australia

Clinical Best Solutions Sp. z.o.o Spolka Komandytowa; 🇵🇱 Warszawa, Poland

Medical Center for Specialized Medical Help in Cardiovascular Diseases OOD; 🇧🇬 Sofia, Bulgaria

Specialized Hospital for Active Treatment of Cardiology; 🇧🇬 Varna, Bulgaria

Kawartha Cardiology Clinical Trials; 🇨🇦 Peterborough, Ontario, Canada

CardioVasc HR; 🇨🇦 Saint-Jean-sur-Richelieu, Quebec, Canada

Discovery Clinical Services, Ltd; 🇨🇦 Victoria, Canada

Special Hospital for Medical Rehabilitation Krapinske Toplice; 🇭🇷 Krapinske Toplice, Croatia

Vseobecna fakultni nemocnice v Praze; 🇨🇿 Praha, Czechia

Kutaisi Primary Health Care Center #1; 🇬🇪 Kutaisi, Georgia

JSC Curatio; 🇬🇪 Tbilisi, Georgia

Ltd Tbilisi Heart Center; 🇬🇪 Tbilisi, Georgia

kfgn | Site Operations & Services GmbH - Berlin-Mitte; 🇩🇪 Berlin, Germany

East Texas Cardiology, PA; 🇺🇸 Houston, Texas, United States

Angiocardiac Care of Texas; 🇺🇸 Houston, Texas, United States

Texas Heart Institute; 🇺🇸 Houston, Texas, United States

Southwest Clinical Trials; 🇺🇸 Houston, Texas, United States

BioStar Clinical Research; 🇺🇸 Houston, Texas, United States

Texas Center for Drug Development; 🇺🇸 Houston, Texas, United States

Osrodek Badan Klinicznych LabMed Agnieszka Karczmarczyk, Filip Karczmarczyk Spólka Cywilna; 🇵🇱 Szczecin, Poland

Franziskus Hospital Berlin; 🇩🇪 Berlin, Germany

MVZ am Küchwald GmbH; 🇩🇪 Chemnitz, Germany

Klinisches Forschungszentrum Dr. Hagemann; 🇩🇪 Essen, Germany

ClinPhenomics CVC GmbH; 🇩🇪 Frankfurt, Germany

Diabetologikum DDG Ludwigshafe; 🇩🇪 Ludwigshafen, Germany

Tagore Medical Center; 🇭🇺 Balatonfüred, Hungary

HMC Westeinde; 🇳🇱 Den Haag, Netherlands

Centrum Medyczne ZDROWA; 🇵🇱 Kraków, Poland

Futuremeds Olsztyn; 🇵🇱 Olsztyn, Poland

Ostrowieckie Centrum Medyczne spólka cywilna Anna Olech-Cudzik; 🇵🇱 Ostrowiec Swietokrzyski, Poland

ZOZ w Olawie, Oddzial Chorob Wewnetrznych; 🇵🇱 Oława, Poland

NZOZ Neuro-Kard - Ilkowski i Partnerzy Spólka Partnerska Lekarzy; 🇵🇱 Poznań, Poland

ETG Siedlce- Lukmed 2 Sp. z o.o.; 🇵🇱 Siedlce, Poland

NZOZ Pro Cordis Sopockie Centrum Badan Kardiologicznych; 🇵🇱 Sopot, Poland

Prywatny Gabinet Lekarski Jacek Gessek; 🇵🇱 Toruń, Poland

ETG Warszawa- MCM Polimedica 2 Sp. z o.o.; 🇵🇱 Warsaw, Poland

FutureMeds Warszawa Centrum; 🇵🇱 Warszawa, Poland

FutureMeds Sp. z o.o; 🇵🇱 Wrocław, Poland

KO - MED Centra Kliniczne Sp. z o.o., Osrodek Badan Klinicznych w Zamosciu; 🇵🇱 Zamość, Poland

ETG Lodz - Santa Sp. z. o.o.; 🇵🇱 Łódź, Poland

DIADA s.r.o.; 🇸🇰 Bardejov, Slovakia

Univerzitna nemocnica Bratislava; 🇸🇰 Bratislava, Slovakia

Kardiologicka ambulancia NsP, n.o.; 🇸🇰 Brezno, Slovakia

Univerzitna nemocnica Martin; 🇸🇰 Martin, Slovakia

Kardiocentrum Nitra s.r.o.; 🇸🇰 Nitra, Slovakia

Iatros International; 🇿🇦 Bloemfontein, South Africa

Medivasa, s.r.o., Angiologicka a kardiologicka ambulancia; 🇸🇰 Žilina, Slovakia

Tiervlei Trial Centre (TTC); 🇿🇦 Cape Town, South Africa

TREAD Research - Department of Cardiology; 🇿🇦 Cape Town, South Africa

Dr JM Engelbrecht Trial Site; 🇿🇦 Somerset West, South Africa

Mediclinic Victoria; 🇿🇦 Tongaat, South Africa

Helderberg Research Institute; 🇿🇦 Somerset West, South Africa

Hospital General Universitario de Alicante Dr. Balmis; 🇪🇸 Alicante, Spain

Hospital Universitario de A Coruna; 🇪🇸 A Coruna, Spain

Hounslow Medical Centre; 🇬🇧 Hounslow, United Kingdom

Columbus Clinical Services; 🇺🇸 Miami, Florida, United States

Finlay Medical Research Corp; 🇺🇸 Miami, Florida, United States

A+ Research Inc; 🇺🇸 Miami, Florida, United States

Ezy Medical Research; 🇺🇸 Miami, Florida, United States

ProLive Medical Research; 🇺🇸 Miami, Florida, United States

AB Clinical Trials; 🇺🇸 Las Vegas, Nevada, United States

Advanced Biomedical Research of America; 🇺🇸 Las Vegas, Nevada, United States

The First Affiliated Hospital of Bengbu Medical College; 🇨🇳 Bengbu, China

Meridian Clinical Research - Cincinnati, OH; 🇺🇸 Cincinnati, Ohio, United States

Meridian Clinical Research - Springfield, OH; 🇺🇸 Cincinnati, Ohio, United States

Sun Research Institute; 🇺🇸 San Antonio, Texas, United States

San Antonio Premier Internal Medicine; 🇺🇸 San Antonio, Texas, United States

Wasatch Clinical Research; 🇺🇸 Salt Lake City, Utah, United States

Elite Clinical Studies; 🇺🇸 Phoenix, Arizona, United States

Kansas Nephrology Research Institute; 🇺🇸 Wichita, Kansas, United States

West Houston Area Clinical Trial Consultants; 🇺🇸 Wichita, Kansas, United States

Hutchinson Clinic; 🇺🇸 Hutchinson, Kansas, United States

Lillestol Research LLC; 🇺🇸 Fargo, North Dakota, United States

Shaare Zedek Medical Center; 🇮🇱 Jerusalem, Israel

Godstrup Regional Hospital (Gødstrup); 🇩🇰 Herning, Denmark

Cardiology Associates of Fairfield County; 🇺🇸 Norwalk, Connecticut, United States

Medical Arts Health Research Group - North Vancouver; 🇨🇦 North Vancouver, British Columbia, Canada

Clinical Research Institute of Arizona, LLC; 🇺🇸 Sun City West, Arizona, United States

Mass General Brigham Pentucket Medical Associates - Haverhill; 🇺🇸 Haverhill, Massachusetts, United States

Cardiology and Medicine Clinic; 🇺🇸 Little Rock, Arkansas, United States

Cardiovascular Associates Research, LLC - Covington, LA; 🇺🇸 Covington, Louisiana, United States

Advocate Health and Hospitals Corporation; 🇺🇸 Oakbrook Terrace, Illinois, United States

Cambridge Medical Trials; 🇺🇸 Alexandria, Louisiana, United States

MHAT Dr. Ivan Seliminski AD; 🇧🇬 Sliven, Bulgaria

Oakland Medical Research Center; 🇺🇸 Troy, Michigan, United States

BTC of New Bedford; 🇺🇸 New Bedford, Massachusetts, United States

Advanced Cardiology Associates; 🇺🇸 Rochester Hills, Michigan, United States

Southern Clinical Research, LLC; 🇺🇸 Zachary, Louisiana, United States

Revival Research Institute; 🇺🇸 Southgate, Michigan, United States

Meir Medical Center; 🇮🇱 Kfar Saba, Israel

Clinical Trials of America; 🇺🇸 West Monroe, Louisiana, United States

Northeast Cardiology Associates; 🇺🇸 Bangor, Maine, United States

Obudai Egeszsegugyi Centrum - Budapest; 🇭🇺 Budapest, Hungary

Clinexpert Kft.; 🇭🇺 Budapest, Hungary

General Hospital Dr Josip Bencevic; 🇭🇷 Slavonski Brod, Croatia

Cardioclinic Digomi Medical Center-; 🇬🇪 Tbilisi, Georgia

Tbilisi Heart and Vascular Clinic Ltd; 🇬🇪 Tbilisi, Georgia

The First Medical Center LTD; 🇬🇪 Tbilisi, Georgia

Obudai Egeszsegugyi Centrum - Zalaegerszeg; 🇭🇺 Zalaegerszeg, Hungary

Rabin Medical Center, Beilinson Hospital; 🇮🇱 Petach Tikva, Israel

ETG Zamosc - Pro Life Medica Sp. z o.o; 🇵🇱 Zamosc, Poland

Porcika Klinik; 🇭🇺 Hodmezovasarhely, Hungary

Medifarma-98 Kft; 🇭🇺 Nyiregyhaza, Hungary

dr Vasas Szilard Haziorvosi Rendelo; 🇭🇺 Nyíregyháza, Hungary

The Lady Davis Carmel Medical Center; 🇮🇱 Haifa, Israel

Zaans Medisch Centrum; 🇳🇱 Zaandam, Netherlands

CENTRUM MEDYCZNE INTERCOR Sp. z o.o.; 🇵🇱 Bydgoszcz, Poland

IPR Hungary Kft; 🇭🇺 Miskolc, Hungary

INSTYTUT CENTRUM ZDROWIA MATKI POLKI - Klinika Kardiologii i Wad Wrodzonych Doroslych; 🇵🇱 Łódź, Poland

Cardio D&R, S.R.O. Kosice; 🇸🇰 Košice, Slovakia

KardioLEV s. r. o.; 🇸🇰 Levoča, Slovakia

Emergency Cardiology Center by Academician G. Chapidze Ltd; 🇬🇪 Tbilisi, Georgia

Pharma4 Trial Kft; 🇭🇺 Gyongyos, Hungary

Somogy Varmegyei Kaposi Mor Oktato Korhaz; 🇭🇺 Kaposvar, Hungary

dr Nagy Laszlo Kardiologiai Maganrendeles es Klinikai Vizsgalohely; 🇭🇺 Orosháza, Hungary

Coromed SMO Kft; 🇭🇺 Pecs, Hungary

Kokura Memorial Hospital; 🇯🇵 Fukuoka, Japan

Showa University Northern Yokohama Hospital; 🇯🇵 Kanagawa, Japan

Sakurabashi Watanabe Hospital; 🇯🇵 Osaka, Japan

Tokyo Saiseikai Central Hospital; 🇯🇵 Tokyo, Japan

Semmelweis Egyetem - Szent Rokus Klinikai Tomb; 🇭🇺 Budapest, Hungary

LTD Adapti; 🇬🇪 Tbilisi, Georgia

Multiprofile Clinic Consilium Medulla LTD; 🇬🇪 Tbilisi, Georgia

Kistarcsai Flor Ferenc Korhaz; 🇭🇺 Kistarcsa, Hungary

Shamir Medical Center (Assaf Harofeh); 🇮🇱 Zerifin, Israel

Japan Community Health Care Organization Kyushu Hospital; 🇯🇵 Fukuoka, Japan

Komatsu Municipal Hospital; 🇯🇵 Ishikawa, Japan

Osaka Medical and Pharmaceutical University Hospital; 🇯🇵 Osaka, Japan

Istishari Hospital; 🇯🇴 Amman, Jordan

Rode Kruis Ziekenhuis; 🇳🇱 Beverwijk, Netherlands

Groene Hart Ziekenhuis; 🇳🇱 Gouda, Netherlands

Elkerliek Ziekenhuis - Locatie Helmond; 🇳🇱 Helmond, Netherlands

Canisius-Wilhelmina Ziekenhuis (CWZ); 🇳🇱 Nijmegen, Netherlands

Centrum Medyczne OMEDICA Jaroslaw Opiela i Beata Opiela s. j.; 🇵🇱 Poznan, Poland

Rabin Medical Center, Beilinson Hospital - Internal Medicine B; 🇮🇱 Petach Tikva, Israel

Ziv Medical Center; 🇮🇱 Safed, Israel

Ishikawa Prefectural Central Hospital; 🇯🇵 Ishikawa, Japan

National Cerebral and Cardiovascular Center Research Institute; 🇯🇵 Osaka, Japan

St. Jansdal Ziekenhuis; 🇳🇱 Harderwijk, Netherlands

Albert Schweitzer Ziekenhuis - Location Zwijndrecht; 🇳🇱 Zwijndrecht, Netherlands

Centrum Medyczne Pratia Bydgoszcz; 🇵🇱 Bydgoszcz, Poland

Indywidualna Specjalistyczna Praktyka Lekarska w Dziedzinie Kardiologii, lek. med. Krzysztof Cymerman; 🇵🇱 Gdynia, Poland

FutureMeds Lodz; 🇵🇱 Łódź, Poland

Stredoslovensky ustav srdcovych a cievnych chorob, a.s.; 🇸🇰 Banská Bystrica, Slovakia

Medispektrum s.r.o., Diabetologicka a metabolicka ambulancia; 🇸🇰 Bratislava, Slovakia

JAL s.r.o.; 🇸🇰 Trnava, Slovakia

The Sakakibara Heart Institute of Okayama; 🇯🇵 Okayama, Japan

Albert Schweitzer Ziekenhuis - Location Dordrecht; 🇳🇱 Dordrecht, Netherlands

Treant Zorggroep; 🇳🇱 Hoogeveen, Netherlands

VieCuri Medisch Centrum; 🇳🇱 Venlo, Netherlands

SALVIA Lekston i Madej s.j.; 🇵🇱 Katowice, Poland

FutureMeds Targowek; 🇵🇱 Warszawa, Poland

Narodowy Instytut Kardiologii Stefana kardynala Wyszynskiego - Panstwowy Instytut Badawczy, Poradnia Prewencji i Leczenia Chorob Metabolicznych, Zaklad Epidemiologii, Prewencji Chorób Ukladu Krazeni; 🇵🇱 Warszawa, Poland

Thyreomedical s.r.o.; 🇸🇰 Bardejov, Slovakia

Nihon University Itabashi Hospital; 🇯🇵 Tokyo, Japan

Abdali Hospital; 🇯🇴 Amman, Jordan

Academic Medical Center - Department of Vascular Medicine; 🇳🇱 Amsterdam, Netherlands

Diakonessenhuis - Locatie Utrecht; 🇳🇱 Utrecht, Netherlands

Ewa Mirek-Bryniarska Specjalistyczna Praktyka Lekarska; 🇵🇱 Krakow, Poland

Aka-Med Centrum Spólka Z Ograniczona Odpowiedzialnoscia; 🇵🇱 Ruda Śląska, Poland

ETG Skierniewice - ClinMedica Research Sp. z o.o.; 🇵🇱 Skierniewice, Poland

Medical KG, s.r.o. - Ambulancia vnutorneho lekarstva; 🇸🇰 Piešťany, Slovakia

Medispol, s.r.o.; 🇸🇰 Presov, Slovakia

Interna SK, s.r.o., Kardiologicka a interna ambulancia; 🇸🇰 Svidník, Slovakia

4 Wojskowy Szpital Kliniczny z Poliklinika Samodzielny Publiczny ZOZ we Wroclawiu; 🇵🇱 Wrocław, Poland

Wroclawska Grupa Medyczna Pankiewicz Spolka Jawna; 🇵🇱 Wrocław, Poland

Alian, s.r.o., Kardiologicka ambulancia; 🇸🇰 Bardejov, Slovakia

Medical group Kosice, s.r.o. - Kardiologicka a Interna ambulancia; 🇸🇰 Kosice, Slovakia

KARDIO 1 s.r.o.; 🇸🇰 Lucenec, Slovakia

Interna a diabetologicka ambulancia - IN - DIA s.r.o., MUDr. Livia Tomasova; 🇸🇰 Lucenec, Slovakia

Kardiomed s.r.o.; 🇸🇰 Lučenec, Slovakia

Medi M and M sro; 🇸🇰 Moldava nad Bodvou, Slovakia

Tatratrial s.r.o; 🇸🇰 Roznava, Slovakia

Mounts Bay Medical; 🇬🇧 Penzance, Cornwall, United Kingdom

Fondazione IRCCS Policlinico San Matteo; 🇮🇹 Pavia, Italy

Istituto Clinico Humanitas; 🇮🇹 Rozzano, Italy

Central Alabama Research; 🇺🇸 Birmingham, Alabama, United States

Ascension - Cardiology Specialists of Birmingham; 🇺🇸 Birmingham, Alabama, United States

Cardiovascular Associates of the Southeast, LLC; 🇺🇸 Birmingham, Alabama, United States

BayCare Health System; 🇺🇸 Tampa, Florida, United States

Mediclub Georgia; 🇬🇪 Tbilisi, Georgia

Wake Forest University Health Sciences; 🇺🇸 Winston-Salem, North Carolina, United States

Biofortis, Inc; 🇺🇸 Addison, Illinois, United States

Advanced Cardiovascular LLC; 🇺🇸 Alexander City, Alabama, United States

The Heart Center Research; 🇺🇸 Huntsville, Alabama, United States

Eastern Shore Research Institute, LLC; 🇺🇸 Fairhope, Alabama, United States

Mobile Heart Specialists; 🇺🇸 Mobile, Alabama, United States

Syed Research Consultants; 🇺🇸 Sheffield, Alabama, United States

Hope Clinical Research LLC; 🇺🇸 Canoga Park, California, United States

Titan Medical Research - Oceanside; 🇺🇸 Encinitas, California, United States

American Institute of Research; 🇺🇸 Los Angeles, California, United States

Westside Medical Associates of Los Angeles; 🇺🇸 Beverly Hills, California, United States

Clinical Trials Research; 🇺🇸 Lincoln, California, United States

Torrance Clinical Research Institute Inc.; 🇺🇸 Lomita, California, United States

Qway Research; 🇺🇸 Hialeah, Florida, United States

East Coast Institute for Research; 🇺🇸 Jacksonville, Florida, United States

New Generation of Medical Research; 🇺🇸 Hialeah, Florida, United States

East Coast Institute for Research - Jacksonville Monroe St; 🇺🇸 Jacksonville, Florida, United States

East Coast Institute for Research - Jacksonville University Blvd; 🇺🇸 Jacksonville, Florida, United States

East Coast Institute for Research- Lake City; 🇺🇸 Lake City, Florida, United States

New Generation of Medical Research - Naples; 🇺🇸 Naples, Florida, United States

Med Research of Florida, LLC; 🇺🇸 Miami, Florida, United States

Ocala Research Institute; 🇺🇸 Ocala, Florida, United States

Ormond Beach Clinical Research LLC; 🇺🇸 Ormond Beach, Florida, United States

Headlands Research; 🇺🇸 Sarasota, Florida, United States

JSV Clinical Research Study, Inc; 🇺🇸 Tampa, Florida, United States

Clinical Research of Central Florida; 🇺🇸 Winter Haven, Florida, United States

Cardiology Partners Clinical Research Institute; 🇺🇸 Wellington, Florida, United States

Atlanta Diabetes Associates; 🇺🇸 Atlanta, Georgia, United States

East Coast Institute for Research - Canton; 🇺🇸 Canton, Georgia, United States

Atlanta Heart Specialists; 🇺🇸 Cumming, Georgia, United States

Javara Inc - SouthCoast Health; 🇺🇸 Savannah, Georgia, United States

Cardiology Care Clinic of Lake Oconee; 🇺🇸 Eatonton, Georgia, United States

Alta Pharmaceutical Research Center; 🇺🇸 Dunwoody, Georgia, United States

Endocrine Research Solutions, Inc; 🇺🇸 Roswell, Georgia, United States

IMA Clinical Research, PC; 🇺🇸 Chicago, Illinois, United States

Clinical Investigation Specialists; 🇺🇸 Kenosha, Wisconsin, United States

Herman Clinical Research; 🇺🇸 Suwanee, Georgia, United States

Midwest Cardiovascular Research and Education Foundation; 🇺🇸 Elkhart, Indiana, United States

Apex Medical Research; 🇺🇸 Hazel Crest, Illinois, United States

Community Health Network-Anderson; 🇺🇸 Anderson, Indiana, United States

Cardiovascular Research of Northwest Indiana, LLC; 🇺🇸 Munster, Indiana, United States

ASHA Clinical Research - Munster, LLC; 🇺🇸 Munster, Indiana, United States

West Broadway Clinic; 🇺🇸 Council Bluffs, Iowa, United States

Research Integrity; 🇺🇸 Owensboro, Kentucky, United States

Medstar Health Research Institute; 🇺🇸 Hyattsville, Maryland, United States

Javara Inc - Healthy Steps; 🇺🇸 Chevy Chase, Maryland, United States

Optimal Research, LLC; 🇺🇸 Rockville, Maryland, United States

McLaren Macomb Regional Medical Center; 🇺🇸 Mount Clemens, Michigan, United States

Aa Mrc, Llc; 🇺🇸 Flint, Michigan, United States

Healthy Heart Cardiology; 🇺🇸 Grand Rapids, Michigan, United States

IMA Clinical Research - St. Louis, MO; 🇺🇸 Saint Louis, Missouri, United States

Sierra Clinical Research; 🇺🇸 Las Vegas, Nevada, United States

Montana Medical Research, Inc.; 🇺🇸 Missoula, Montana, United States

Meridian Clinical Research- Lincoln, NE; 🇺🇸 Lincoln, Nebraska, United States

Advanced Heart Care, LLC; 🇺🇸 Bridgewater, New Jersey, United States

Cardio Metabolic Institute; 🇺🇸 Somerset, New Jersey, United States

Inspira Medical Centers; 🇺🇸 Mullica Hill, New Jersey, United States

New Mexico Clinical Research & Osteoporosis Center Inc.; 🇺🇸 Albuquerque, New Mexico, United States

Saratoga Clinical Research; 🇺🇸 Saratoga Springs, New York, United States

DiGiovanna Institute for Medical Education and Research; 🇺🇸 North Massapequa, New York, United States

Great Lakes Medical Research, LLC; 🇺🇸 Westfield, New York, United States

Meridian Clinical Research- Endwell, NY; 🇺🇸 Vestal, New York, United States

Southgate Medical Group; 🇺🇸 West Seneca, New York, United States

Javara Inc - Tryon Medical Partners LLC; 🇺🇸 Charlotte, North Carolina, United States

Medication Management, LLC; 🇺🇸 Greensboro, North Carolina, United States

Burke Primary Care; 🇺🇸 Morganton, North Carolina, United States

Diabetes and Endocrinology Consultants, P.C; 🇺🇸 Morehead City, North Carolina, United States

Wilmington Health Associates; 🇺🇸 Wilmington, North Carolina, United States

Nexgen Research; 🇺🇸 Lima, Ohio, United States

PriMed Clinical Research; 🇺🇸 Dayton, Ohio, United States

SV Research; 🇺🇸 Marion, Ohio, United States

Advanced Medical Research (AMR); 🇺🇸 Maumee, Ohio, United States

Preferred Primary Care Physicians Group - Pleasant Hills; 🇺🇸 Pittsburgh, Pennsylvania, United States

Lynn Health Science Institute - East; 🇺🇸 Oklahoma City, Oklahoma, United States

Altoona Center for Clinical Research; 🇺🇸 Duncansville, Pennsylvania, United States

South Carolina Clinical Research LLC; 🇺🇸 Orangeburg, South Carolina, United States

Frontier Clinical Research; 🇺🇸 Smithfield, Pennsylvania, United States

Piedmont Research Partners, LLC; 🇺🇸 Fort Mill, South Carolina, United States

Abington Medical Specialists, P.C. dba AMS Cardiolog; 🇺🇸 Horsham, Pennsylvania, United States

Clinical Research Collaborative, LLC; 🇺🇸 Cumberland, Rhode Island, United States

Monument Health Clinical Research, a department of Monument Health Rapid City Hospital, Inc; 🇺🇸 Rapid City, South Dakota, United States

Stern Cardiovascular Foundation, Inc; 🇺🇸 Germantown, Tennessee, United States

Cardiovascular Research of Knoxville; 🇺🇸 Powell, Tennessee, United States

Hillcrest Clinical Research; 🇺🇸 Simpsonville, South Carolina, United States

Chattanooga Research & Medicine, PLLC; 🇺🇸 Chattanooga, Tennessee, United States

Holston Medical Group; 🇺🇸 Kingsport, Tennessee, United States

New Phase Research & Development; 🇺🇸 Knoxville, Tennessee, United States

PharmaTex Research, LLC; 🇺🇸 Amarillo, Texas, United States

Southwest Family Medicine Associates; 🇺🇸 Dallas, Texas, United States

Javara Inc - Bridge Creek Family Medicine; 🇺🇸 Cypress, Texas, United States

Texas Health Research & Education Institute; 🇺🇸 Dallas, Texas, United States

Private Practice - O. Alejandro Brusco, MD FACE PA; 🇺🇸 Corpus Christi, Texas, United States

David Turbay, MD, PLLC; 🇺🇸 El Paso, Texas, United States

Javara Inc - Texas Health Care Family Physicians; 🇺🇸 Fort Worth, Texas, United States

Valley Institute of Research - Fort Worth; 🇺🇸 Fort Worth, Texas, United States

West Houston Area Clinical Trial Consultants, LLC; 🇺🇸 Katy, Texas, United States

Milton Haber, M.D; 🇺🇸 Laredo, Texas, United States

Tapia Internal Medicine Clinic; 🇺🇸 Paris, Texas, United States

North Hills Medical Research, Inc.; 🇺🇸 North Richland Hills, Texas, United States

Styde Research; 🇺🇸 Plano, Texas, United States

Bandera Family HealthCare Research, LLC (BFHC); 🇺🇸 San Antonio, Texas, United States

Alpine Research Organization, Inc.; 🇺🇸 Clinton, Utah, United States

Physicians' Research Options (PRO); 🇺🇸 Draper, Utah, United States

Burke Internal Medicine & Research; 🇺🇸 Burke, Virginia, United States

Carient Heart & Vascular; 🇺🇸 Manassas, Virginia, United States

York Clinical Research LLC; 🇺🇸 Norfolk, Virginia, United States

MultiCare Institute for Research and Innovation- Tacoma; 🇺🇸 Tacoma, Washington, United States

Universal Research Group LLC; 🇺🇸 Tacoma, Washington, United States

Royal Adelaide Hospital; 🇦🇺 Adelaide, Australia

Flinders Medical Centre; 🇦🇺 Bedford Park, Australia

Campbelltown Hospital; 🇦🇺 Campbelltown, Australia

The Prince Charles Hospital; 🇦🇺 Chermside, Australia

Bridge Family Practice; 🇦🇺 Halls Creek, Australia

Baker Heart and Diabetes Institute; 🇦🇺 Melbourne, Australia

Monash Health; 🇦🇺 Clayton, Australia

The Alfred Hospital; 🇦🇺 Melbourne, Australia

Austin Health; 🇦🇺 Heidelberg, Australia

Redcliffe Hospital; 🇦🇺 Redcliffe, Australia

Griffith University; 🇦🇺 Southport, Australia

Wollongong Hospital (Illawarra Shoalhaven Local Health District); 🇦🇺 Wollongong, Australia

MHAT Aytos EOOD Department of Internal Diseases; 🇧🇬 Aytos, Bulgaria

UMHAT Deva Maria; 🇧🇬 Burgas, Bulgaria

Medical Center Viva Feniks; 🇧🇬 Dobrich, Bulgaria

MHAT Haskovo AD; 🇧🇬 Haskovo, Bulgaria

Medical Center Doctor Staykov EOOD; 🇧🇬 Burgas, Bulgaria

MHAT Sveti Ivan Rilski; 🇧🇬 Gorna Oryahovitsa, Bulgaria

MHAT City Clinic - Sveti Georgi EOOD; 🇧🇬 Montana, Bulgaria

Medical Center - Cordis OOD; 🇧🇬 Pleven, Bulgaria

MHAT Heart and Brain Pleven; 🇧🇬 Pleven, Bulgaria

Medical Center for Rehabilitation and Sports Medicine I - Plovdiv EOOD; 🇧🇬 Plovdiv, Bulgaria

Medical Center Rusemed EOOD; 🇧🇬 Ruse, Bulgaria

UMHAT Sveti Georgi EA; 🇧🇬 Plovdiv, Bulgaria

SHATC Medica Cor EAD; 🇧🇬 Ruse, Bulgaria

MHAT Sveta Sofia EOOD; 🇧🇬 Sofia, Bulgaria

Multiprofile Hospital for Active Treatment (MHAT)- Silistra; 🇧🇬 Silistra, Bulgaria

Diagnostic and Consulting Center 22 - Sofia; 🇧🇬 Sofia, Bulgaria

DCC "Ascendent"; 🇧🇬 Sofia, Bulgaria

National Multiprofile Transport Hospital Tsar Boris Treti - Cardiology Clinic; 🇧🇬 Sofia, Bulgaria

Diagnostic consultative center 24; 🇧🇬 Sofia, Bulgaria

MC Doctor Kalchev OOD; 🇧🇬 Sofia, Bulgaria

CardioArt Medical Center; 🇧🇬 Stara Zagora, Bulgaria

Diagnostic Consultative Center Chaika; 🇧🇬 Varna, Bulgaria

Medical Centre Medcross; 🇧🇬 Sofia, Bulgaria

Diagnostic Consulting Center Convex EOOD; 🇧🇬 Sofia, Bulgaria

"Medical Center Medic" OOD; 🇧🇬 Sofia, Bulgaria

Multiprofile Hospital for Active Treatment National Cardiology Hospital; 🇧🇬 Sofia, Bulgaria

Medical Center Zara - Med; 🇧🇬 Stara Zagora, Bulgaria

UMHAT Prof. Dr. Stoyan Kirkovich; 🇧🇬 Stara Zagora, Bulgaria

Medical Center Plazmamed Clinic; 🇧🇬 Varna, Bulgaria

Medical Center Nevromedics; 🇧🇬 Veliko Tarnovo, Bulgaria

Medical Center Medica Plus OOD; 🇧🇬 Veliko Tarnovo, Bulgaria

Medical Center Velingrad 2017 EOOD; 🇧🇬 Velingrad, Bulgaria

Winnipeg Clinic; 🇨🇦 Winnipeg, Manitoba, Canada

Medical Arts Health Research Group - Kamloops; 🇨🇦 Kamloops, British Columbia, Canada

LMC Diabetes & Endocrinology Ltd. - Thornhill; 🇨🇦 Concord, Ontario, Canada

The Medical Arts Health Research Group - Penticton; 🇨🇦 Penticton, British Columbia, Canada

Ecogene-21; 🇨🇦 Chicoutimi, Quebec, Canada

Dr. James Cha; 🇨🇦 Oshawa, Ontario, Canada

KMH Cardiology & Diagnostic Centres - Hamilton; 🇨🇦 Stoney Creek, Ontario, Canada

Diex Recherche Victoriaville; 🇨🇦 Victoriaville, Quebec, Canada

Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Estrie -Centre hospitalier universitaire de Sherbrooke (CHUS); 🇨🇦 Sherbrooke, Quebec, Canada

Diex Recherche Trois-Rivieres, Inc; 🇨🇦 Trois-Rivières, Quebec, Canada

Centre de recherche clinique de Laval; 🇨🇦 Laval, Canada

KMH Cardiology & Diagnostic Centres - Mississauga; 🇨🇦 Mississauga, Canada

Brampton Clinical Trials; 🇨🇦 Brampton, Canada

Guangdong Provincial People's Hospital; 🇨🇳 Guangzhou, China

Affiliated Hospital of Chifeng University; 🇨🇳 Chifeng, China

Peking University First Hospital; 🇨🇳 Beijing, China

The First People's Hospital of Changde City; 🇨🇳 Changde, China

Institut Universitaire de Cardiologie et de Pneumologie De Quebec; 🇨🇦 Quebec, Canada

The Second People's Hospital of Changzhou; 🇨🇳 Changzhou, China

Shunde Hospital of Southern Medical University; 🇨🇳 Foshan, China

Heilongjiang Provincial Hospital; 🇨🇳 Harbin, China

The First affiliated Hospital of Nanyang Medical College; 🇨🇳 Nanyang, China

Daqing People's Hospital; 🇨🇳 Daqing, China

The First Affiliated Hospital of Nanyang Medical College - 2nd site; 🇨🇳 Nanyang, China

Ningbo First Hospital; 🇨🇳 Ningbo, China

Panjin Liaoyou Gem Flower Hospital; 🇨🇳 Panjin, China

Tianjin Fourth Central Hospital; 🇨🇳 Tianjin, China

Pingxiang People's Hospital; 🇨🇳 Pingxiang, China

Xianyang Hospital of Yan 'an University; 🇨🇳 Xianyang, China

Xi'an Gaoxin Hospital; 🇨🇳 Xi'an, China

People's Hospital of Tianjin; 🇨🇳 Tianjin, China

Zibo City Linzi District People's Hospital; 🇨🇳 Zibo, China

The Third Affiliatied Hospital of Xinxiang Medical University; 🇨🇳 Xinxiang, China

General Hospital Karlovac; 🇭🇷 Karlovac, Croatia

Polyclinic Solmed; 🇭🇷 Zagreb, Croatia

Cevni ambulance - MATMED s.r.o.; 🇨🇿 Hodonin, Czechia

Medicus Services SRO; 🇨🇿 Brandýs Nad Labem, Czechia

Amkardia sro; 🇨🇿 Brno, Czechia

University Hospital Center Zagreb; 🇭🇷 Zagreb, Croatia

Kardiologicka ambulance Brno s.r.o.; 🇨🇿 Brno, Czechia

Nemocnice Havlickuv Brod, p.o.; 🇨🇿 Havlickuv Brod, Czechia

Hornicka nemocnice s poliklinikou Bilina s.r.o.; 🇨🇿 Bílina, Czechia

Lunacor, s.r.o. - Centrum pro choroby srdce a cev - Otrokovice; 🇨🇿 Otrokovice, Czechia

Edumed s.r.o.; 🇨🇿 Náchod, Czechia

KARDIOLOGIE - LIBEREC s.r.o.; 🇨🇿 Liberec, Czechia

Lunacor s.r.o. - Centrum pro choroby srdce a cev; 🇨🇿 Kroměříž, Czechia

MUDr. Tomas Edelsberger - diabetologicka ambulance; 🇨🇿 Krnov, Czechia

PreventaMed s.r.o.; 🇨🇿 Olomouc, Czechia

CCR Ostrava s.r.o.; 🇨🇿 Ostrava, Czechia

Kardiologie COR s.r.o.; 🇨🇿 Prague, Czechia

Ustredni vojenska nemocnice; 🇨🇿 Prague, Czechia

Krajska nemocnice T. Bati; 🇨🇿 Zlín, Czechia

Health Ltd; 🇬🇪 Batumi, Georgia

Fakultní nemocnice v Motole; 🇨🇿 Praha, Czechia

StudyCor Oy; 🇫🇮 Jyväskylä, Finland

Satucon Oy Kuopio; 🇫🇮 Kuopio, Finland

Aalborg University Hospital; 🇩🇰 Aalborg, Denmark

Sydvestjysk Hospital; 🇩🇰 Esbjerg, Denmark

Viborg Regional Hospital; 🇩🇰 Viborg, Denmark

Bispebjerg Hospital; 🇩🇰 Kobenhavn, Denmark

JSC Evex Hospitals - Batumi Referral Hospital; 🇬🇪 Batumi, Georgia

Amager Hospital; 🇩🇰 Copenhagen, Denmark

Turku University Hospital; 🇫🇮 Turku, Finland

Bokhua Memorial Cardiovascular Center LTD; 🇬🇪 Tbilisi, Georgia

David Metreveli Medical Centre Lt; 🇬🇪 Tbilisi, Georgia

LTD Vitamed; 🇬🇪 Tbilisi, Georgia

Ltd Georgian-Dutch Hospital; 🇬🇪 Tbilisi, Georgia

LTD Israeli -Georgian Medical Research Clinic Healthycore; 🇬🇪 Tbilisi, Georgia

National Center for Diabetes Research; 🇬🇪 Tbilisi, Georgia

Diabetespraxis Dr. Braun; 🇩🇪 Berlin, Germany

VivaMedi; 🇬🇪 Tbilisi, Georgia

Kardiologische Praxis Dr. med. univ. Wolfgang Jungmair; 🇩🇪 Bad Homburg, Germany

Kardiologisch-Angiologische Praxis - Herzzentrum Bremen; 🇩🇪 Bremen, Germany

Gemeinschaftspraxis Diabeteszentrum Dortmund; 🇩🇪 Dortmund, Germany

St Johannes Hospital Dortmund; 🇩🇪 Dortmund, Germany

Universitaetsklinikum Carl Gustav Carus Dresden; 🇩🇪 Dresden, Germany

ZKS - Zentrum Klinische Studien Sudbrandenburg GmbH; 🇩🇪 Elsterwerda, Germany

Kfgn | Site Operations & Services GmbH - Dresden; 🇩🇪 Dresden, Germany

Katholisches Krankenhaus St. Johann Nepomuk; 🇩🇪 Erfurt, Germany

Zentrum für Klinische Studien (diabetes-falkensee.de); 🇩🇪 Falkensee, Germany

Studienzentrum Bocholderstrasse; 🇩🇪 Essen, Germany

Diabeteszentrum Hamburg West (DZHW) / Gemeinschaftspraxis Dr. Wendisch, Dr. Dahl und Prof. Dr. Aberle; 🇩🇪 Hamburg, Germany

St. Josefskrankenhaus Heidelberg GmbH; 🇩🇪 Heidelberg, Germany

Universitaetsklinikum Schleswig-Holstein Campus Kiel; 🇩🇪 Kiel, Germany

Velocity Clinical Research Leipzig GmBH; 🇩🇪 Leipzig, Germany

CDG Studienambulanz Dr. Hartard; 🇩🇪 München, Germany

Kliniken Maria Hilf GmbH Krankenhaus St. Franziskus; 🇩🇪 Monchengladbach, Germany

Praxis Drs. Haggenmiller/Jeserich; 🇩🇪 Nuernberg, Germany

Praxis Reinfeld Mitte; 🇩🇪 Reinfeld, Germany

RED-Institut GmbH; 🇩🇪 Oldenburg In Holstein, Germany

Qualiclinic Kft; 🇭🇺 Budapest, Hungary

INFO-MED Leipzig GmbH; 🇩🇪 Zwenkau, Germany

Gemeinschaftspraxis Dr. med. Josef und Dr. med. Wilma Grosskopf; 🇩🇪 Wallerfing, Germany

Klinikum München Klinik Neuperlach; 🇩🇪 München, Germany

Del-pesti Centrumkorhaz; 🇭🇺 Budapest, Hungary

Lausmed Kft; 🇭🇺 Baja, Hungary

Herz Kreislauf Zentrum - Klinikum Hersfeld Rotenburg GmbH; 🇩🇪 Rotenburg, Germany

Forschungszentrum Ruhr; 🇩🇪 Witten, Germany

Studienzentrum Brinkum; 🇩🇪 Stuhr, Germany

MED-TIMA Kft; 🇭🇺 Budapest, Hungary

Dr Lakatos Ferenc Belgyogyaszati-Kardiologiai Maganrendelo; 🇭🇺 Békéscsaba, Hungary

Semmelweis Egyetem - Varosmajori Sziv es Ergyogyaszati Klinika; 🇭🇺 Budapest, Hungary

Belinus Bt; 🇭🇺 Debrecen, Hungary

High Tech Medical Kft; 🇭🇺 Budapest, Hungary

CRU Hungary Kft.; 🇭🇺 Encs, Hungary

BKS Research Kft.; 🇭🇺 Hatvan, Hungary

Pest M. Flór F. Kórház V. Belgy. Oszt; 🇭🇺 Kistarcsa, Hungary

Barzilai Medical Center; 🇮🇱 Ashkelon, Israel

Bnai Zion Medical Center; 🇮🇱 Haifa, Israel

Rambam Health Care Campus; 🇮🇱 Haifa, Israel

Hadassah Hebrew University Medical Center - Cardiology - The Heart Institute; 🇮🇱 Jerusalem, Israel

Galilee Medical Cente; 🇮🇱 Nahariyya, Israel

The BARUCH PADEH Medical Center, Poriya; 🇮🇱 Poriyya, Israel

Kaplan Medical Center; 🇮🇱 Reẖovot, Israel

IRCCS Ospedale San Raffaele; 🇮🇹 Milano, Italy

Azienda Ospedaliero-Universitaria di Ferrara-Arcispedale Sant'Anna; 🇮🇹 Ferrara, Italy

Azienda Ospedaliera Universitaria Federico II; 🇮🇹 Napoli, Italy

Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone; 🇮🇹 Palermo, Italy

Azienda Ospedaliera Santa Maria di Terni; 🇮🇹 Terni, Italy

Chiba University Hospital; 🇯🇵 Chiba, Japan

New Tokyo Heart Clinic; 🇯🇵 Chiba, Japan

Hiroshima Prefectural Hospital; 🇯🇵 Hiroshima, Japan

National Hospital Organization Takasaki General Medical Center; 🇯🇵 Gunma, Japan

Hiroshima University Hospital; 🇯🇵 Hiroshima, Japan

Hyogo Prefectural Harima-Himeji General Medical Center; 🇯🇵 Hyōgo, Japan

Niigata University Medical & Dental Hospital; 🇯🇵 Niigata, Japan

Public Central Hospital of Matto lshikawa; 🇯🇵 Ishikawa, Japan

Yokohama Minami Kyousai Hospital; 🇯🇵 Kanagawa, Japan

Saiseikai Senri Hospital; 🇯🇵 Osaka, Japan

Irbid Specialty Hospital; 🇯🇴 Irbid, Jordan

Latgales Medical Center; 🇱🇻 Daugavpils, Latvia

D. Saulites-Kandevicas Private Practice; 🇱🇻 Liepaja, Latvia

SIA ANIO; 🇱🇻 Daugavpils, Latvia

Pharmaceutical Research Center -Jordan University of Science & Technology/King Abdulla University Hospital - Cardiology; 🇯🇴 Irbid, Jordan

Ziekenhuis Rijnstate; 🇳🇱 Arnhem, Netherlands

Pauls Stradins Clinical University Hospital Riga; 🇱🇻 Riga, Latvia

Vidzemes Hospital; 🇱🇻 Valmiera, Latvia

Reinier de Graaf Gasthuis; 🇳🇱 Delft, Netherlands

Het Van Weel-Bethesda Ziekenhuis; 🇳🇱 Dirksland, Netherlands

Ziekenhuis Gelderse Vallei; 🇳🇱 Ede, Netherlands

Maxima Medisch Centrum; 🇳🇱 Eindhoven, Netherlands

Leids Universitair Medisch Centrum; 🇳🇱 Leiden, Netherlands

Stichting Radboud Universitair Medisch Centrum; 🇳🇱 Nijmegen, Netherlands

Franciscus Gasthuis & Vlietland - Locatie Gasthuis; 🇳🇱 Rotterdam, Netherlands

Centrum Medyczne Kermed - Renata Bijata-Bronisz I Ewa Kowalinska Spólka Jawna; 🇵🇱 Bydgoszcz, Poland

DIAB Serwis Popenda Spólka Jawna; 🇵🇱 Chorzów, Poland

NZOZ Twoje Zdrowie EL Sp. z o.o.; 🇵🇱 Elbląg, Poland

Uniwersyteckie Centrum Kliniczne, I Klinika Kardiologii; 🇵🇱 Gdansk, Poland

Indywidualna Specjalistyczna Praktyka Lekarska dr n. med. Adam Grzybowski; 🇵🇱 Gdańsk, Poland

Samodzielny Publiczny Specjalistyczny Szpital Zachodni im. Jana Pawla II; 🇵🇱 Grodzisk Mazowiecki, Poland

Centrum Medyczne Pratia Katowice; 🇵🇱 Katowice, Poland

Silmedic Sp. z o.o.; 🇵🇱 Katowice, Poland

Pratia MCM Krakow; 🇵🇱 Krakow, Poland

Krakowski Szpital Specjalistyczny im. Jana Pawla II - Oddzial Kliniczny Kardiologii Interwencyjnej z Pododdzialem Intenyswengo Nadzoru Kardiologicznego; 🇵🇱 Kraków, Poland

Krakowskie Centrum Medyczne Sp. z o.o.; 🇵🇱 Kraków, Poland

Clinical Best Solutions - Lublin; 🇵🇱 Lublin, Poland

KO - MED Centra Kliniczne Lublin II; 🇵🇱 Lublin, Poland

ETG Lublin - Pro Life Medica Sp. z o.o; 🇵🇱 Lublin, Poland

Szpital Sw. Anny w Miechowie; 🇵🇱 Miechów, Poland

Pomorskie Centra Kardiologiczne Sp. z o.o., SKA - Mragowo; 🇵🇱 Mragowo, Poland

Indywidualna Specjalistyczna Praktyka Lekarska Wlodzimierz Kus; 🇵🇱 Łódź, Poland

Human-Care s.r.o; 🇸🇰 Kosice, Slovakia

JM-INTERNA, s.r.o., Ambulancia vnutorneho lekarstva; 🇸🇰 Dolny Kubin, Slovakia

WCR - Bara Cardiology; 🇿🇦 Johannesburg, South Africa

Hospital Universitari de Bellvitge; 🇪🇸 Barcelona, Spain

Hospital Universitario Vall d'Hebron; 🇪🇸 Barcelona, Spain

Hospital Universitario Torrecardenas; 🇪🇸 Almeria, Spain

Hospital del Mar; 🇪🇸 Barcelona, Spain

Hospital Universitario Virgen de las Nieves; 🇪🇸 Granada, Spain

Hospital Clinico Universitario de Santiago; 🇪🇸 Santiago de Compostela, Spain

Hospital Universitario Virgen de la Victoria; 🇪🇸 Malaga, Spain

Hospital General Universitario Gregorio Maranon; 🇪🇸 Madrid, Spain

Hospital Universitario Joan XXIII de Tarragona; 🇪🇸 Tarragona, Spain

Hospital Universitario Virgen Macarena; 🇪🇸 Sevilla, Spain

Hospital Alvaro Cunqueiro; 🇪🇸 Vigo, Spain

Hospital Universitario Miguel Servet; 🇪🇸 Zaragoza, Spain

Hospital Universitario Reina Sofia; 🇪🇸 Córdoba, Spain

Atlantic Medical Group; 🇬🇧 Penzance, Cornwall, United Kingdom

FutureMeds - Soho Road Health Centre; 🇬🇧 Birmingham, United Kingdom

Waterloo Medical Centre; 🇬🇧 Blackpool, United Kingdom

Hospital Clinico Universitario de Valencia; 🇪🇸 Valencia, Spain

Ulster Hospital; 🇬🇧 Belfast, United Kingdom

Birmingham Heartlands Hospital; 🇬🇧 Birmingham, United Kingdom

University Hospital of Wales; 🇬🇧 Cardiff, United Kingdom

Fowey River Practice; 🇬🇧 Fowey, United Kingdom

Futuremeds - CPS Research; 🇬🇧 Glasgow, United Kingdom

FutureMeds - Ely Bridge Surgery; 🇬🇧 Cardiff, United Kingdom

Panthera - London North; 🇬🇧 Enfield Town, United Kingdom

Darlington Memorial Hospital; 🇬🇧 Durham, United Kingdom

Panthera - Glasgow; 🇬🇧 Glasgow, United Kingdom

The Good Practice; 🇬🇧 London, United Kingdom

St. Bartholomew's Hospital; 🇬🇧 London, United Kingdom

Beacon Medical Group; 🇬🇧 Plymouth, United Kingdom

Chelsea and Westminster Hospital; 🇬🇧 London, United Kingdom

Luton and Dunstable University Hospital; 🇬🇧 Luton, United Kingdom

Craigavon Area Hospital; 🇬🇧 Portadown, United Kingdom

Panthera - Manchester; 🇬🇧 Rochdale, United Kingdom

Panthera - Sheffield; 🇬🇧 Sheffield, United Kingdom

Panthera - Preston; 🇬🇧 Preston, United Kingdom

Queens Hospital; 🇬🇧 Romford, United Kingdom

Sandwell General Hospital; 🇬🇧 West Bromwich, United Kingdom

FutureMeds - Bridle Road Clinic; 🇬🇧 Wirral, United Kingdom

Worcestershire Royal Hospital; 🇬🇧 Worcester, United Kingdom

Centrum pro zdravi - kardiologie s.r.o.; 🇨🇿 Brno, Czechia

InterKardio ML s.r.o.; 🇨🇿 Mariánské Lázně, Czechia

Heart and Vascular Center at Methodist Hospital; 🇺🇸 Saint Louis Park, Minnesota, United States

Invesclinic; 🇺🇸 Fort Lauderdale, Florida, United States

Amicis Research Center-Northridge; 🇺🇸 Northridge, California, United States

Javara Inc - Wake Forest Health Network Family Physicians - Sunset Avenue; 🇺🇸 Asheboro, North Carolina, United States

Advanced Research Institute Inc; 🇺🇸 New Port Richey, Florida, United States

Innovative Research of West Florida; 🇺🇸 Clearwater, Florida, United States

Community Health Network; 🇺🇸 Indianapolis, Indiana, United States

East Coast Institute for Research - Perimeter Park Court; 🇺🇸 Jacksonville, Florida, United States

Javara Inc - Highland Woods Health; 🇺🇸 The Woodlands, Texas, United States

Louisville Metabolic and Atherosclerosis Research Center (L-MARC); 🇺🇸 Louisville, Kentucky, United States

NSC Research; 🇺🇸 Johns Creek, Georgia, United States

The Iowa Clinic - Cardiovascular Services; 🇺🇸 Des Moines, Iowa, United States

The Research Group of Lexington, LLC; 🇺🇸 Lexington, Kentucky, United States

Chear Center LLC; 🇺🇸 Bronx, New York, United States

Central Texas Clinical Research; 🇺🇸 Austin, Texas, United States

Accelemed Research Institute; 🇺🇸 Austin, Texas, United States

Dominion Medical Associates; 🇺🇸 Richmond, Virginia, United States

Arcturus Healthcare; 🇺🇸 Troy, Michigan, United States

Michigan Heart; 🇺🇸 Ypsilanti, Michigan, United States

Louisiana Heart Center; 🇺🇸 Slidell, Louisiana, United States