Study on the characteristics of intestinal microecological community and its correlation with syndromes in patients with early age-related macular degeneration (AMD)
- Conditions
- Early age-related macular degeneration
- Registration Number
- ITMCTR2100004463
- Lead Sponsor
- Eye Hospital, China Academy of Chinese Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
AMD patients group
1. In accordance with the diagnostic criteria of early AMD: Beckman initiative for macular research classification committee-Clinical classification of age-related macular degeneration and Clinical pathway of age-related macular degeneration in China
2. Aged 50 to 80 years;
3. Agree to participate in the trial and provide written informed consent.
Control group
1. Aged 50 to 80 years;
2. Those without AMD-related pathological changes, glaucoma, uveitis or other fundus diseases, which involves the macular area and retinal vessels;
3. Those without diabetes, hypertension, malignant tumors, mental diseases, immune system diseases and other diseases, all indicators of physical examination are within the normal range;
4. Those without infectious diseases or antibiotics taken in the past 4 weeks;
5. Those without any intestinal related diseases including acute gastroenteritis in the past 4 weeks;
6. Those without having taken probiotics/prebiotics or other micro-ecological regulators, Chinese medicines (including Chinese patent medicine, decoctions with clear ingredients, or remedies with unknown ingredients) in the past 4 weeks, or overeating foods with antibacterial effects (such as chili,ginger,garlic,etc.);
7. Agree to participate in the trial and provide written informed consent.
AMD patients group
1. Those with diabetes,hypertension,malignant tumors,mental diseases,immune system diseases and other diseases;
2. Those with glaucoma,uveitis or other fundus diseases,which involves the macular area and retinal vessels;
3. Those with infectious diseases or antibiotics taken in the past 4 weeks;
4. Those with any intestinal related diseases including acute gastroenteritis in the past 4 weeks;
5. Those with having taken probiotics/prebiotics or other micro-ecological regulators, Chinese medicines (including Chinese patent medicine, decoctions with clear ingredients,or remedies with unknown ingredients) in the past 4 weeks,or overeating foods with antibacterial effects (such as chili, ginger,garlic,etc.);
6. Those with other stages of AMD.
Study & Design
- Study Type
- Observational study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method