ISRCTN78042015进行中（未招募）2 期
Deep brain stimulation for disorders of addiction: mechanisms and a pilot blinded randomized cross-over placebo-controlled trial
适应症
试验速览
- 阶段
- 2 期
- 状态
- 进行中（未招募）
- 入组人数
- 12
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Diagnosis of treatment-refractory opioid use disorder (OUD) or alcohol use disorder (AUD) (DSM-5 diagnosis)
- •2. Comorbid nicotine dependence, other psychoactive use disorder permissible as long as OUD or AUD is the primary diagnosis
- •3. At least 5 years duration
- •4. 3+ failed abstinence attempts
- •5. Failed psychotherapy and standard pharmacotherapy
- •6. Age 18 to 60 years old
- •7. MRI compatible
- •8. Capable of informed consent
排除标准
- •1. Deep brain stimulation or neurosurgical contraindication (e.g. unable to tolerate general anaesthesia, risk of bleeding)
- •2. History of repeated falls
- •3. Other major psychiatric (e.g. schizophrenia, bipolar disorder or severe major depression) or neurologic disorder
- •4. Major head injury
- •5. Marked cognitive impairment or cortical atrophy
研究者
相似试验
撤回
不适用
Effects of rTMS and tDCS Treatment on Brain Function, Craving and Relapse PreventionAddictionNCT03549065Medical University of South Carolina
尚未招募
不适用
Deep brain stimulation(DBS) for intractable obsessive-compulsive disorders(OCDs). randomized crossover trial and open-label trialIntractable obsessive-compulsive disordersJPRN-UMIN000022969Hamamatsu University School of Medicine20
暂停
2 期
Deep brain stimulation for intractable obsessive-compulsive disorders.Intractable obsessive-compulsive disordersJPRN-jRCTs042180039ozaki Takao20
已完成
4 期
Advancing addiction treatment using neuromodulation: a rTMS enhanced CBT trialalcoholverslavingalcohol addiction10034726Alcohol dependenceNL-OMON47612Academisch Medisch Centrum80
Unknown
不适用
Advancing addiction treatmentalcohol addiction / alcohol verslavingrepetitive Transcranial Magnetic Stimulation (rTMS) / repetitieve Transcraniële Magnetische Stimulatietreatment / behandelingfunctional Magnetic Resonance Imaging (fMRI)NL-OMON22620AMC, department of psychiatry, Addiction care80