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The Effect of local Injection of Cortone on Pain preception after Root Canal treatment of teeth with Irreversible Pulpits

Phase 3
Conditions
Teeth with irreversible pulpitis.
Other and unspecified diseases of pulp and periapical tissues
Registration Number
IRCT2016053028173N2
Lead Sponsor
Tabriz University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
213
Inclusion Criteria

All the teeth of maxillary and mandibular jaws diagnosed as irreversible pulpitis; with normal probing depth; tenderness; no history of using drugs such as analgesics (except ibuprofen), analgesic and anti-anxiety in the past two weeks; no medical history; no contraindication for prescribing cortisone; teeth with at least dilated periodontal ligament in periapical radiography; no dental implants in studied dental quadrant; approved vitality with pulp tests and cold spray; teeth with clinically diagnosed as irreversible pulpitis with response to electric pulp tester; longitudinal and magnified response (10 seconds); moderate to severe pain after the removal of the ice test cotton ball.
Exclusion criteria: Systemic disease or maxillary sinusitis; unstable heart disease; high blood pressure; sensitivity to anesthetic lidocaine, epinephrine and latex; contraindications ofr lidocaine and epinephrine application; facial or oral paresthesia; use of any painkillers, Sedatives, anti-anxiety and corticosteroids during 2 weeks before treatment (except using 1.6 g of ibuprofen daily in past two days); pregnancy; breastfeeding; unreturnable teeth; teeth with full-coverage of restoration; over filling or over instrumentation during treatment; contraindications of using topical corticosteroids; diabetes; long-term steroid use; false positives vitality test observed after tooth necrosis; need to inject opal interpol for increasing the anesthesia.

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Pain relief. Timepoint: 6, 12, 24, 48, 72 hours and 7 days after injection. Method of measurement: Visual Analog Scale (VAS).
Secondary Outcome Measures
NameTimeMethod
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