CTRI/2020/12/029761招募中不适用
Covid-19 outcome in patients with Connective Tissue Disease with or without Interstitial Lung Disease.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- CT THORAX SEVERITY SCORE
研究概览
简要总结
COVID AFFECTS CELLS WITH ACE2 RECEPTOR. THERE IS REDUCED ANGIOTENSIN 2 MRNA AND ITS ACTIVITY IN LUNG TISSUE OF IDIOPATHIC PULMONARY FIBROSIS AND BLEOMYCIN INDUCED LUNG FIBROSIS.WE ASSUME REDUCED COVID INFECTION DUE TO THIS. CTD MAY CAUSE INTERSTITIAL FIBROSIS AND SO DOES COVID, SO THERE MAY BE MORE LUNG DAMAGE. TREATMENT OF CONNECTIVE TISSUE DISEASE INVOLVES ANTI-INFLAMMATORY DRUGS WHICH MAY BE PROTECTIVE FOR COVID 19 INFECTION. SO THE OUTCOME NEEDS TO BE EVALUATED AND STUDIED.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •All cases of Connective Tissue Disease with interstitial lung disease associated with Covid19 infection -All cases of Connective Tissue Disease without interstitial lung disease associated with Covid19 infection.
排除标准
- •Co-morbidity like Chronic Kidney Disease,Chronic Liver Disesase.
- •Patient who does not give consent for study.
结局指标
主要结局
CT THORAX SEVERITY SCORE
时间窗: 0 AND 12WEEKS
次要结局
- 6MinuteWalkDistance,ErythrocyteSedimentationRate(0,12WEEKS)
研究者
研究点 (1)
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