CTRI/2019/10/021513
Completed
Phase 4
Comparison of the efficacy of oxybutynin with that of mirabegron as an add-on therapy to tamsulosin in patients with persistent storage symptoms presumed to be due to benign prostatic hyperplasia : A randomized controlled trial
JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION RESEARCH0 sites96 target enrollmentTBD
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- Health Condition 1: N401- Benign prostatic hyperplasia withlower urinary tract symptoms
- Sponsor
- JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION RESEARCH
- Enrollment
- 96
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Male patients aged 50 years or older with LUTS presumed to be due BPH having urinary urgency at least once per week and a total OAB symptom score (OABSS) ââ?°Â¥ 3 points after ââ?°Â¥ 8 weeks treatment with tamsulosin 0\.4mg od
Exclusion Criteria
- •1\.PVR \> 100 ml
- •2\.Q max \< 5 ml/s
- •3\.Prior diagnosis of neurogenic bladder
- •4\.Performance of clean intermittent catheterization,
- •5\.Severe bladder diverticulum or urethral stricture,
- •6\.Planning to have a child,
- •7\.Suspected prostate or bladder malignancy
- •8\.Previous urethral surgery or prior diagnosis of urethral stricture disease.
- •9\.Previous intra pelvic irradiation,
- •10\.Suspected recurrent urinary infection,
Outcomes
Primary Outcomes
Not specified
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