Colonic Polypectomy in Cirrhotic Patients With Portal Hypertension

Active, not recruiting

• Conditions: Liver Cirrhosis; Portal Hypertension Related to Cirrhosis; Polyp of Colon; Polypectomy

• Registration Number: NCT06832826
• Lead Sponsor: Zagazig University

Brief Summary

The goal of this retrospective cohort study is to evaluate the risk of post-polypectomy bleeding following the colonoscopy resection of lower gastrointestinal polyps in patients with liver cirrhosis with portal hypertension. The main question it aims to answer is:

Does the risk of bleeding increase after colonoscopy polypectomy in patients with liver cirrhosis with portal hypertension?

Participants will be subjected to polypectomy of any colonic polyps.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-01-14
• Primary Completion: 2024-06-26
• Study First Submitted: 2025-01-12
• Status Verified: 2025-02
• Study First Submitted QC: 2025-02-16
• Last Update Submitted: 2025-02-16
• Study First Posted: 2025-02-18
• Last Update Posted: 2025-02-18
• Study Completion: 2025-03

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• All liver cirrhosis patients with portal hypertension and colonic polyps

Exclusion Criteria

• Patients with platelet count less than 50,000/µL.
• Patients with hemoglobin levels less than 8 g/dL.
• Prothrombin Time more than 20 seconds.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Immediate post polypectomy bleeding (IPPB)	During procedure
Delayed post polypectomy bleeding (DPPB)	24 hours to 14 days

Secondary Outcome Measures

Name	Time	Method
Type of polyps in patients with liver cirrhosis and portal hypertension	14 days	Using the Paris classification system for polyps

Trial Locations

Locations (1)

Zagazig University Hospital; 🇪🇬 Zagazig, Sharkia, Egypt